int J Clin Exp Med. 2015 Aug 15;8(8):14085-9. eCollection 2015.
Abstract
BACKGROUND:
Endometriosis
is a common gynecological disease defined as the presence of
endometrioid tissue (glands and stroma) outside the uterus. About 30 to
40% patients with endometriosis are infertile. In traditional Chinese medical system, endometriosis associated infertility
is mostly caused by kidney deficiency and blood stasis. The herb of
reinforcing kidney and removing blood stasis is designed to treat the
disease.
MATERIAL AND METHODS:
All
the 80 up-to-standard patients were divided into two different groups
exactly according to the random principle. They were treated with
hormone and traditional Chinese
medical herb separately. After half year's therapy, all the patients
received one year's follow-up. Their transvaginal ultrasonographic
changes, serum hormone levels and pregnancy rate were recorded to
analysis the effect.
RESULTS:
No
significant difference happened in two groups' demographic and clinical
characteristics (P > 0.05). After the treatment, the effect on serum
hormone levels and specific markers are significant (P < 0.05). The
transvaginal ultrasonographic changes were positive, too. The text on
hepatic and renal function confirmed to the safety of the herb. Compared
to hormone therapy, the traditional Chinese medical herb is safe and effective for endometriosis patients with infertility.
CONCLUSION:
Compared with hormone therapy, traditional Chinese medical herb's two-staged therapy is effective and safe for endometriosis patients with infertility.
KEYWORDS:
Endometriosis; infertility; mifepristone; traditional Chinese medicine
