Relationship of dietary vitamin B1 and the level of risk for dementia

Koomesh

Volume 17, Issue 2, Winter 2016, Pages 343-351

Open Access

  (Article)

Kiamanesh, R.^a, 

Shadnoush, M.^b , 

Mehrabi, Y.^c

^a  The International Branch of Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran
^b  School of Medicine, Semnan University of Medical Sciences, Semnan, Iran
^c  Dept. of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran 

View additional affiliations

View references (27)

Abstract

Introduction: Vitamin B1 (Thiamin) is an essential cofactor for enzymes involving in brain glucose metabolism. The purpose of this study was to define the association between dietary vitamin B1 and the level of risk for dementia. Materials and Methods: In this study we used an age and sex matched case control method, consisting of 120 men and women of 50 years (± 2) of age and older. Data were collected at ‘Iran Alzheimer Association’, Tehran, in 2013. The experimental cases (with dementia) and controls (normal) (n = 60) were randomly selected. Dietary information was collected using ‘food frequency questionnaire’ and a 24-hour food recall questionnaire, and analyzed using the food processor Nutritionist IV. Results: The cases mean intake of vitaminB1 from the food sources was less than controls, before and after adjustment for confounding factors. In the effect of total energy intake method, the highest tertiles for vitamin B1 intake and the risk for dementia was obtained at (OR: 0.02; 95% CI, 0.004 to 0.14), with a P-value < 0.001 in comparison to the first tertile. Conclusion: The findings of this study suggest that a high vitaminB1 intake from the food sources may reduce the risk of dementia. Maintaining the effective levels through the consumption of specific foods is a viable option to prevent dementiaoccurrence and progression. © 2015, Singapore Medical Association. All rights reserved.

Author keywords

Dementia; Diet; Vitamin B1

Indexed keywords

EMTREE drug terms: thiamine

EMTREE medical terms: adult; Article; assessment of humans; controlled study; dementia; dietary intake; female; food frequency questionnaire; food recall questionnaire; human; male; middle aged; vitamin supplementation

Chemicals and CAS Registry Numbers: thiamine, 59-43-8, 67-03-8

ISSN: 16087046Source Type: Journal Original language: Persian

Document Type: Article

Publisher: Semnan University of Medical Sciences

References (27)

View in search results format

• Page
 
• • Export |
  • Print |
  • E-mail |
  • Create bibliography

• 
  1

  Association, A.P.
  (1994) Diagnostic and Statistical Manual of Mental Disorders. Cited 12710 times.
  4th ed: Washington, DC
  

  •  
• 
  2

  Nozari, N., Ferri, C.P., Farin, F., Noroozian, M., Salehi, M., Seyedian, M., Prince, M.

  Validation of the 10/66 Dementia Research Group's 10/66 dementia diagnosis in Iran
  (2009) International Psychogeriatrics, 21 (3), pp. 604-605. Cited 2 times.
  doi: 10.1017/S104161020900845X
  

  • View at Publisher
• 
  3

  (2015) Prevent Alzheimer’s Disease: What Do We Know?
  National Institute on Aging
  

  •  
• 
  4

  Morris, M., Wang, Y., Sacks, F.M., Bennett, D.A., Aggarwal, N.T.
  MIND diet associated with reduced incidence of Alzheimer's disease.
  (2015) Alzheimers Dement, 15, pp. 1552-1560.
  

  •  
• 
  5

  Dumont, M., Lin, M.T., Beal, M.F.

  Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease
  (2010) Journal of Alzheimer's Disease, 20 (SUPPL.2), pp. S633-S643. Cited 54 times.
  doi: 10.3233/JAD-2010-100507
  

  • View at Publisher
• 
  6

  Harper, C.

  Thiamine (vitamin B1) deficiency and associated brain damage is still common throughout the world and prevention is simple and safe!
  (2006) European Journal of Neurology, 13 (10), pp. 1078-1082. Cited 69 times.
  doi: 10.1111/j.1468-1331.2006.01530.x
  

  • View at Publisher
• 
  7

  David, W., Candless, M.C.
  (2009) Thiamin Deficiency and Associated Clinical Disorders
  North Chicago IL USA Humana Press
  

  •  
• 
  8

  Roger, F.
  Thiamin defeciency and brain disorders
  (2007) Nutr Res Rev, 16, pp. 277-2784.
  

  •  
• 
  9

  Hazell, A.S., Butterworth, R.F.

  Update of cell damage mechanisms in thiamine deficiency: Focus on oxidative stress, excitotoxicity and inflammation
  (2009) Alcohol and Alcoholism, 44 (2), pp. 141-147. Cited 66 times.
  doi: 10.1093/alcalc/agn120
  

  • View at Publisher
• 
  10

  Gibson, G.E., Hirsch, J.A., Cirio, R.T., Jordan, B.D., Fonzetti, P., Elder, J.

  Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes
  (2013) Molecular and Cellular Neuroscience, 55, pp. 17-25. Cited 15 times.
  doi: 10.1016/j.mcn.2012.09.001
  

  • View at Publisher
• 
  11

  Manavifar, L., Nemati Karimooy, H., Nejat Shokuhi, A., Sheerdel, A., Shakeri, M., Mahjoob, M.
  Neurocognitive and psychologic bio-markers in old people in mashhad
  (2009) Iran Irje, 5, pp. 40-48.
  (Persian)
  

  •  
• 
  12

  Jack Jr., C.R., Knopman, D.S., Jagust, W.J., Shaw, L.M., Aisen, P.S., Weiner, M.W., Petersen, R.C., (...), Trojanowski, J.Q.

  Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
  (2010) The Lancet Neurology, 9 (1), pp. 119-128. Cited 1398 times.
  doi: 10.1016/S1474-4422(09)70299-6
  

  • View at Publisher
• 
  13

  Bryant, S.E., Lacritz, L., Hall, J., Warin, S.C., Chan, W., Khodr, Z.G.
  Validation of the new interpretive guidelines for score in the NACC database
  (2010) Philos Trans R Soc Land B Biol Sci, 360, pp. 2335-2345.
  

  •  
• 
  14

  Bubber, P., Haroutunian, V., Fisch, G., Blass, J.P., Gibson, G.E.

  Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
  (2005) Annals of Neurology, 57 (5), pp. 695-703. Cited 275 times.
  doi: 10.1002/ana.20474
  

  • View at Publisher
• 
  15

  Zhang, Q., Yang, G., Li, W., Fan, Z., Sun, A., Luo, J., Ke, Z.-J.

  Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides
  (2011) Neurobiology of Aging, 32 (1), pp. 42-53. Cited 26 times.
  doi: 10.1016/j.neurobiolaging.2009.01.005
  

  • View at Publisher
• 
  16

  Winblad, B., Gauthier, S., Åström, D., Stender, K.

  Memantine benefits functional abilities in moderate to severe Alzheimer's disease
  (2010) Journal of Nutrition, Health and Aging, 14 (9), pp. 770-774. Cited 15 times.
  doi: 10.1007/s12603-010-0122-x
  

  • View at Publisher
• 
  17

  Nardone, R., Höller, Y., Storti, M., Christova, M., Tezzon, F., Golaszewski, S.
  Thiamine defeciency induced neurochemical, neuroanatomical and neuropsychological alterations: A reappraisal
  (2013) Sci World J, 2013, pp. 382-400.
  

  •  
• 
  18

  Wojda, U., Salinska, E., Kuznicki, J.

  Calcium ions in neuronal degeneration
  (2008) IUBMB Life, 60 (9), pp. 575-590. Cited 114 times.
  doi: 10.1002/iub.91
  

  • View at Publisher
• 
  19

  Ke, Z.-J., Gibson, G.E.

  Selective response of various brain cell types during neurodegeneration induced by mild impairment of oxidative metabolism
  (2004) Neurochemistry International, 45 (2-3), pp. 361-369. Cited 54 times.
  doi: 10.1016/j.neuint.2003.09.008
  

  • View at Publisher
• 
  20

  Gibson, G.E., Blass, J.P.

  Thiamine-dependent processes and treatment strategies in neurodegeneration
  (2007) Antioxidants and Redox Signaling, 9 (10), pp. 1605-1619. Cited 49 times.
  doi: 10.1089/ars.2007.1766
  

  • View at Publisher
• 
  21

  Kopelman, M.D.
  What does a comparison of the alcoholic Korsakoff syndrome and thalamic infarction tell us about thalamic amnesia?
  (2014) Neurosci Behav Rev, 54, pp. 44-56. Cited 4 times.
  

  •  
• 
  22

  Vinh Quc Lu'O'Ng, K., Nguyen, L.T.H.

  Role of thiamine in Alzheimer's disease
  (2011) American Journal of Alzheimer's Disease and other Dementias, 26 (8), pp. 588-598. Cited 8 times.
  doi: 10.1177/1533317511432736
  

  • View at Publisher
• 
  23

  Nolan, K.A., Black, R., Sheu, K.F., Langberg, J., Blass, J.P.
  A trial of thiamine in Alzheimer’s disease
  (2012) Arch Neurol, 48, pp. 81-83.
  

  •  
• 
  24

  Murray, F.
  (2012) Minimizing the Risk of Alzheimer's Disease
  New York: Algora Publishing - Health & Fitness
  

  •  
• 
  25

  Jr, J.W.E., Iam, S.H.Z.
  (2012) Present Knowledge in Nutrition. Cited 4 times.
  editors, Wiley-Blackwell
  

  •  
• 
  26

  Rodríguez-Martín, J.L., Qizilbash, N., López-Arrieta, J.M.
  Thiamine for Alzheimer's disease
  (2001) Cochrane Database Syst Rev, 2. Cited 22 times.
  

  •  
• 
  27

  Ollat, H., Laurent, B., Bakchine, S., Michel, B.-F., Touchon, J., Dubois, B.

  Effects of the association of sulbutiamine with an acetylcholinesterase inhibitor in early stage and moderate Alzheimer disease
  (2007) Encephale, 33 (2), pp. 211-215. Cited 10 times.
  

  • View at Publisher

© Copyright 2015 Elsevier B.V., All rights reserved.