Emma Hardie Moringa Cleansing Balm
Moringa Cleansing BalmMoringa seed extract, Wild Sea Fennel and Vitamin
E: Balance, purify and help to minimise the appearance of open pores.
Orange, Neroli and Mandarin extracts: Rejuvenate and revitalise the
skin. Jasmine, Cedarwood and Rose: Help to recondition dull, dry,
dehydrated and mature skins
Wound healing properties of ethyl acetate fraction of Moringa oleifera in normal human dermal fibroblasts.
- 1Laboratory
of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti
Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
- 2Laboratory
of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti
Putra Malaysia, 43400, Serdang, Selangor, Malaysia; Department of Human
Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra
Malaysia, 43400, Serdang, Selangor, Malaysia.
Abstract
BACKGROUND/AIM:
Wounds are the outcome of injuries to the skin
that interrupt the soft tissue. Healing of a wound is a complex and
long-drawn-out process of tissue repair and remodeling in response to
injury. A large number of plants are used by folklore traditions for the
treatment of cuts, wounds and burns. Moringa oleifera (MO) is an herb used as a traditional folk medicine for the treatment of various skin
wounds and associated diseases. The underlying mechanisms of wound
healing activity of ethyl acetate fraction of MO leaves extract are
completely unknown.
MATERIALS AND METHODS:
In
the current study, ethyl acetate fraction of MO leaves was investigated
for its efficacy on cell viability, proliferation and migration (wound
closure rate) in human normal dermal fibroblast cells.
RESULTS:
Results
revealed that lower concentration (12.5 µg/ml, 25 µg/ml, and 50 µg/ml)
of ethyl acetate fraction of MO leaves showed remarkable proliferative
and migratory effect on normal human dermal fibroblasts.
CONCLUSION:
This study suggested that ethyl acetate fraction of MO leaves might be a potential therapeutic agent for skin
wound healing by promoting fibroblast proliferation and migration
through increasing the wound closure rate corroborating its traditional
use.
KEYWORDS:
Active fractions; cell proliferation; migration; natural products; scratch assay
