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Sunday 5 January 2020

Ethnoveterinary Medicine: Present and Future Concepts

Ethnoveterinary Plants and Practices for the Control of Ticks and Tick-Borne Diseases in South Africa
  • January 2020
  • In book: Ethnoveterinary Medicine: Present and Future Concepts
  • Publisher: Springer Nature Switzerland AG
Gender Aspects and Multiple Contexts in Ethnoveterinary Practice and Science
  • December 2019
  • In book: Ethnoveterinary Medicine

Saturday 4 January 2020

ISEE Sessions at APA Central


ISEE will be hosting 2 affiliated group sessions at the 2020 Central Division Meeting of the APA:
Friday, February 28  7:00pm – 10:00pm
Climate Justice
Chair:
Ben Almassi
Speakers:
William Littlefield (Case Western University) – “Utility Gains in Climate Justice”
Marcus Hedahl (US Naval Academy) – “Climate Justice & Moral Psychology: Surprising Stoic Solutions”
Kizito Michael George (Kyambogo University) – “Linking Climate Change to Human Rights and Social Justice: A Critique of the Ethics and Epistemologies of Climate Change Science”
Rachel Fredericks (Ball State University) – “Climate Legacy: A New(ish) Concept for the Climate Crisis”
Saturday, February 29  2:00pm – 5:00pm
Understanding Community
Chair: Megs Gendreau (Centre College)
Speakers:
Connor Kianpour (Georgia State University) – “Dolphin Ownerhood: Nonhuman Persons and Habitative Noninterference”
Sade Hormio (UC Berkeley) – “Climate Change and Responsibility as Members of Collective Agents”
Justin Donhauser (Bowling Green State University) – “Robot Pollinator Ethics”
Zachary Vereb (University of South Florida) – “A Kantian Perspective on Climate Ethics: History and Global Community”

CFP: International Society for Environmental Ethics 17th Annual Summer Meeting


Call for papers on themes concerning
Action and the Climate Crisis
July 6-9, 2020
H.J. Andrews Experimental Forest, Blue River, Oregon
This call for papers solicits 500-word proposals for presentations on any topic in environmental philosophy. However, special attention will be given to proposals for talks concerning issues connected with first-order normative claims, initiatives, and action in response to the range of environmental threats connected to climate change, biodiversity loss, mass extinction, pollution, and ecosystem degradation.
An escalating rhetoric of a “crisis” or “emergency” has accompanied an increase of public awareness about harmful climate impacts and degraded environmental conditions. With some regularity, we hear that observed phenomena either meet or exceed the worst-case scenarios within a suite of possible trajectories. Predicted changes in the natural world are unfolding more rapidly than expected, e.g. loss of Arctic ice, and international pledges to act are simply not being met, as global GHG emissions continue to grow. Empirical studies reveal surprising and deeply troubling information about, for example, the collapse of insect and bird populations, while some powerful right-wing and authoritarian political leaders only exacerbate the problems, e.g. Trump’s withdraw from the Paris Agreement and Bolsonaro’s policies of deforestation and development in the Amazon.
In response, there has been growing youth-led, political engagement, exemplified by the international school strikes for climate action and the U.S. Sunrise Movement, as well as a return to non-violent direct action (e.g., by Extinction Rebellion in the UK). One widespread refrain asserts we have only 12 years to radically transform society, which calls for a mobilization equivalent to those made to fight world wars. How should we think about that? While environmental philosophy has traditionally focused on theory, concepts, and ideological frameworks (e.g. conceptions of intrinsic value, anthropocentrism, and environmental justice), the theme of this conference is to focus on praxis, conduct, behavior, and concrete action: How can philosophy help us understand and engage with conditions that call us to action? How can we do activism well in the climate arena, both strategically and ethically? What will future generations, in retrospect, think we should be doing today?
Proposals prepared for blind review should be submitted via email to Allen Thompson, <allen.thompson@oregonstate.edu> no later than March 1st, 2020. Decisions will be announced by April 15th.

Radical scavenging and antiproliferative effect of novel phenolic derivatives isolated from Nerium indicum against human breast cancer cell line (MCF-7)—an in silico and in vitro approach

Abstract
Multiple drug resistance and increased side effects due to allopathic drugs has warned scientific community with a global alarm to identify molecules from natural sources to combat diseases with minimum or no side effects. The present investigation was aimed to identify and isolate secondary metabolites from traditionally used Nerium indicum using conventional column chromatography which led to the isolation of two compounds, C-I (fractions NB4f1) and C-II (fractions NC13b1). Further characterized, it is elucidated using spectral data and identified as N-(4-hydroxy-phenyl)-2-methoxy-2-phenyl-acetamide, molecular formula C15H15NO3, and molecular weight 257.3 (C-I) and N-(4-hydroxy-phenyl)-2-phenyl-N-phenylacetyl-acetamide, molecular formula C22H19NO3, and molecular weight 345.4 (C-II). Further, the isolated compounds were investigated using in silico approach by Autodock tool with four different proteins specific for cancer and in vitro assessed cell proliferation, and apoptosis against human breast cancer MCF 7 cell line. The results of the in silico model demonstrated potent binding affinity of both compounds with the proteins representing that the isolated molecules could be a drug of choice for cancer. Further, the isolated compounds revealed significant inhibition of cell proliferation (IC50 values 21 μg/mL for C-I, 19 μg/mL for C-II) with induced apoptosis with nuclear condensation effect on the MCF 7 cells in in vitro condition even at very low concentration. Compound treatment to MCF-7 cell line represented bright fetches indicating condensed chromatins and higher level of nuclear fragmentation with DAPI staining, indicating higher cell death due to induced apoptosis and confirmed using flow cytometry analysis representing inhibition of cell proliferation at S phase.
 
https://www.researchgate.net/publication/338281545_Radical_scavenging_and_antiproliferative_effect_of_novel_phenolic_derivatives_isolated_from_Nerium_indicum_against_human_breast_cancer_cell_line_MCF-7-an_in_silico_and_in_vitro_approach

Alternative Antimicrobials: Medicinal Plants and Their Influences on Animal Infectious Diseases

Ethnoveterinary medicine refers to the beliefs, knowledge, methods, practices and techniques used in the promotion of healthcare and well-being for animals. Since the 1940s, antibiotics were fed to livestock animals to boost their productivity by growing them bigger faster and at a cheaper price. Nonetheless, over the years many antibiotics which were once used successfully to attenuate or kill disease-causing microorganisms have now become inefficacious. Additionally, the number of antibiotic leads and novel antibiotics proposed by pharmaceutical companies has stalled considerably. Hence, there is an urgent need to provide newer classes of antibiotics or to derive modern strategies to combat disease-causing microorganisms. This chapter mentions 275 plant species used in different countries around the world to treat infectious ailments in animals. Plants listed in this chapter provide an indication of medicinal plants used in parts of Africa such as in South Africa and Uganda; in Asia such as in India, Nepal, Afghanistan and Pakistan; as well as in other countries such as Brazil and Iran. Interestingly, the results of in vitro studies provide valuable insights with respect to the antimicrobial properties of plants used in traditional medicinal systems over the world. These results can unlock diverse avenues for screening novel compounds, leads or even plant extracts that can be successfully developed as antimicrobial agents.

https://www.researchgate.net/publication/338329556_Alternative_Antimicrobials_Medicinal_Plants_and_Their_Influences_on_Animal_Infectious_Diseases