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Monday, 12 January 2015

Lancet oncology Uncaria tomentosa, the cat's whiskers or claws?


After Columbus' second expedition to Central America in 1493, stories of poison-tipped arrows, and horrifying accounts of death and paralysis soon reached Europe. The poison used to coat the arrows is now known as curare, and is used as a skeletal muscle relaxant because of its action on the nicotinic acetylcholine receptor at the neuromuscular junction. Curare has enchanted American and European botanists since its discovery and was one of the first examples of plant extracts with medicinal valu