Thirteen aqueous extracts (decoctions) used as antidiarrheal in
Kinshasa, Democratic Republic of Congo and their forty two fractions
were submitted to an evaluation for their potential antibacterial
properties against isolated pathogenes bacteria implicated in diarrhea.
Results indicated that five extracts including those from Carica papaya
root, Hensia pulchella leaf, Morinda morindoides leaf, Psidium guayava
leaf, Tithonia diversifolia leaf as well as their respective
ethylacetate fractions rich in flavonoids inhibited the growth of all
tested bacteria with minimum inhibitory and bactericidal concentrations
ranging from 15.62 to 62.50 µg/ml (good activity). Aqueous extracts from
other selected medicinal plants exhibited a combined level of activity
as good (MIC and MBC < 100 µg/ml), moderate (125 < MIC and MBC
< 250 µg/ml and weak (250 < MIC and MBC < 500 µg/ml) or were
inactive (MIC and MBC > 500 µg/ml) against some selected bacteria
according to the case. These results can partly justify and support the
tradition use of these medicinal plants for the preparation of remedies
used for the treatment of diarrhea of bacterial origin.
https://www.researchgate.net/publication/332080239_ANTIBACTERIAL_SCREENING_OF_AQUEOUS_EXTRACTS_OF_SOME_MEDICINAL_PLANT_AND_THEIR_FRACTIONS_USED_AS_ANTIDIARRHEAL_AGENTS_IN_KINSHASA-DEMOCRATIC_REPUBLIC_OF_CONGO_Corresponding_Author
