https://www.researchgate.net/publication/332276325_Efficacy_toxicity_and_lethality_of_plants_with_potential_anthelmintic_activity_in_small_ruminants_in_Brazil
The
use of medicinal plants as a therapeutic method in the control of
diseases has been increasing in animal production. In the case of small
ruminants, the endoparasitic disease is a major concern, since they are
considered the greater sanitary problem, especially when considering the
phenomenon of parasite resistance to the medicines used. Therefore, the
development of alternative methods of endoparasitary control in goats
and sheep has become a pressing need. The use of plants to control
endoparasites can reduce the use of chemical inputs, making more
environmentally sustainable livestock, minimizing the occurrence of
parasitic resistance to conventional medicines and contributing to the
reduction of production costs. In this sense, several studies have been
carried out in order to evaluate the in vitro and in vivo activity of
plants with anthelmintic potential. However, despite the potentiality
found in many studies, the results are sometimes contradictory or do not
replicate in vivo the same efficacy obtained in the in vitro assays.
Another relevant aspect is the low utilization of the lethality and
toxicity tests, which are indispensable so that the knowledge can be
spread and applied by the producers in their herds. Thus, this review
aims to provide the results from studies carried out in Brazil with
extract of plants with potential for control of parasitic disease in
goats and sheep, describing the main evaluated plants species,
mechanisms of action, preparation forms and tests of efficacy, toxicity,
and lethality.
…
