Ethno pharmacology is defined as a slipt up approach for novel drug overture by providing valuable data about medicinal plants in different cultures. Identification and documentation data of medicinal plants in veterinary treatments of north khorasan province in the past, take the aim of this ethno pharmacological study. North khorasan province with different climates and wide diversity in plant species located in the Northeastern of Iran. Ethno veterinary data was collected from rural areas of two city of north khorasan province, Bojnord and Shirval, over an 8-month period in 2017. The medical plants and traditional knowledge of ethno veterinary practices that used for livestock remedy gathered from 20 local informants and practitioners in animal husbandry from the past, by face to face interview and semi-structured questionnaires. In this present investigation, 19 plants founded to be used in treating illness and problems of sheep and cattle. In this research also the amount of number of use (NU), frequency of citation (FC) and Relative cultural importance (RCI) indecies determined.