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Thursday, 25 October 2012

Allium sativum used against poultry respiratory disease



1.  Plants used to treat unspecified poultry respiratory diseases that have activity against influenza virus.

Allium sativum, Andrographis paniculata and Nicotiana glauca exhibit activity against influenza virus either clinically or in vitro.

Allium sativum
Clinically garlic protects mice from influenza and its constituents are antiviral to influenza. Fresh garlic is virucidal against herpes simplex virus types 1 and 2, human rhinovirus type 2, parainfluenza-3, vaccinia virus and vesicular stomatitis virus.  Garlic is immune-modulating and may combat influenza when given prior to infection.

Structure of Andrographolide and the semi synthetic analog of andrographolide, DRF3188
Satyanarayana et al. BMC Cancer 2004 4:26   doi:10.1186/1471-2407-4-26

                                               
Andrographis paniculata
Andrographis paniculata is used to prevent the spread of  respiratory disease in family poultry in India.  Clinical studies on Andrographis paniculata, either alone or in combination with Eleutherococcus senticosis indicate that is effective in reducing the severity of clinical signs associated with respiratory infections including colds, sinusitis and influenza in humans. Andrographis paniculata, or its constituents possess activity against hepatitis B, HIV and respiratory syncytial virus. Andrographis paniculata possesses potent immune-modulating and anti-inflammatory properties, which may account for the amelioration of clinical signs of respiratory disease observed in chickens.