FNS> Vol.4 No.8A, August 2013 |
Antioxidant Properties of Medicinal Plants from Peru
Download as PDF (Size:444KB)
HTML
PP.
71-77
There is a wide diversity of plants and seasonal
crops in Peru, due to the presence of many climatic zones. Numerous
plants are used to cure or prevent diseases. These plants are promising
candidates for functional foods products. The most frequent form in
which they are used is an aqueous infusion or decoction. In this study,
we compared the antioxidant properties of ten Peruvian plants infusions
and investigated their relation to the phenolic content. The studied
plants were: Uncaria tomentosa (cat’s claw), Lepidium meyenii (maca), Berberis vulgaris L. (barberry, agracejo), Phyllantus niruri (chanca piedra), Annona muricata L. (graviola, soursop), Gentianella alborosea (hercampure), Geranium dielsianum (pasuchaca), Tabebuia ochracea (tahuari), Notholaena nivea (“cuti cuti”) and Tiquilia paronychioides
(“flor de arena”). Infusions of all studied plants have shown
antioxidant activity, though there was a large diversity between the
results. The antioxidant properties, determined with DPPH and ABTS
scavenging assays as well as FRAP test, were strongly correlated with
total phenolic content, while there was no correlation with the
carotenoid content.
KEYWORDS
Cite this paper
A. Berłowski, K. Zawada, I. Wawer and K. Paradowska,
"Antioxidant Properties of Medicinal Plants from Peru," Food and Nutrition Sciences, Vol. 4 No. 8A, 2013, pp. 71-77. doi: 10.4236/fns.2013.48A009.
[1] | K. Keplinger, G. Laus, M. Wurm, M. P. Dierich and H. Teppner, “Uncaria tomentosa (Willd.) DC.-Ethnomedicinal Use and New Pharmacological, Toxicological and Botanical Results,” Journal of Ethnopharmacology, Vol. 64, No. 1, 1999, pp. 23-34. doi:10.1016/S0378-8741(98)00096-8 |
[2] | M. E. Heitzman, C. C. Neto, E. Winiarz, A. J. Vaisberg and G. B. Hammond, “Ethnobotany, Phytochemistry and Pharmacology of Uncaria (Rubiaceae),” Phytochemistry, Vol. 66, No. 1, 2005, pp. 5-29. doi:10.1016/j.phytochem.2004.10.022 |
[3] | C. Goncalves, T. Dinis and M. T. Batista, “Antioxidant Properties of Proanthocyanidins of Uncaria tomentosa Bark Decoction: A Mechanism for Anti-Inflammatory Activity,” Phytochemistry, Vol. 66, No. 1, 2005, pp. 89-98. doi:10.1016/j.phytochem.2004.10.025 |
[4] | Y. Wang, Y. Wang, B. McNeil and L. M. Harvey, “Maca: An Andean Crop with Multi-Pharmacological Functions,” Food Research International, Vol. 40, No. 7, 2007 pp. 783-792. doi:10.1016/j.foodres.2007.02.005 |
[5] | G. F. Gonzales, C. Gonzales and C. Gonzales-Castaneda. “Lepidium meyenii (Maca): A Plant from the Highlands of Peru—From Tradition to Science,” Forsch Komplementmed, Vol. 16, No. 6, 2009, pp. 373-380. doi:10.1159/000264618 |
[6] | C. Gonzales, J. Rubio, M. Gasco, Y. Nieto, S. Yucra and G. F. Gonzales, “Effect of Short Term and Long Term Treatments with Three Ecotypes of Lepidium meyenii (maca) on Spermatogenesis in Rats,” Journal of Ethnopharmacology, Vol. 103, No. 3, 2006, pp. 448-454. doi:10.1016/j.jep.2005.08.035 |
[7] | J. Rubio, M. Caldas, S. Dávila, M. Gasco and G. F. Gonzales, “Effect of Three Different Cultivars of Lepidium meyenii (maca) on Learning and Depression in Ovariect-Omized Mice,” BMC Complementary & Alternative Medicine, Vol. 6, No. 1, 2006, pp. 23-30. doi:10.1186/1472-6882-6-23 |
[8] | M. Sandoval, N. N. Okuhama, F. M. Angeles, V. M. Melchor, L. A. Condezo, J. Lao and M. J. S. Miller, “Antioxidant Activity of the Cruciferous Vegetable Maca (Lepidium meyenii),” Food Chemistry, Vol. 79, No. 2, 2002, pp. 207-213. doi:10.1016/S0308-8146(02)00133-4 |
[9] | K. J. Lee, K. Dabrowski, J. Rinchard, C. Gomez, L. Guz and C. Vilchez, “Supplementation of Maca (Lepidium meyenii) Tuber Meal in Diets Improves Growth Rate and Survival of Rainbow Trout Oncorhynchus Mykiss (Walbaum) Alevins and Juveniles,” Aquaculture Research, Vol. 35, No. 3, 2004, pp. 215-223. doi:10.1111/j.1365-2109.2004.01022.x |
[10] | M. Blumenthal, W. R. Busse, A. Goldbert, J. Gruenwald, T. Hall, S. Klein, C. W. Riggins and R. S. Rister, “The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicine,” American Botanical Council, Austin, 1998. |
[11] | J. Brunetton, “Pharmacognosy, Phytochemistry, Medicinal Plants,” Lavoisier Publishing, Paris, 1999. |
[12] | P. Hanachi, S. H. Kua, R. Asmah, G. Motalleb and O. Fauziah, “Cytotoxic Effect of Berberis vulgaris Fruit Extract on the Proliferation of Human Liver Cancer Line (HepG2) and Its Antioxidant Properties,” International Journal of Cancer Research, Vol. 2, No. 1, 2006, pp. 1-9. doi:10.3923/ijcr.2006.1.9 |
[13] | S. Schaffer and M. Heinrich, “Understanding Local Mediterranean Diets: A Multidisciplinary Pharmacological and Ethnobotanical Approach,” Pharmacological Research, Vol. 52, No. 4, 2005, pp. 353-366. doi:10.1016/j.phrs.2005.06.005 |
[14] | R. N. Chopra, S. L. Nayar and I. C. Chopra, “Glossary of Indian Medicinal Plants,” Catholic Press, Ranchi, CSIR, New Delhi, 1986. |
[15] | M. L. Dhar, M. M. Dhar, B. N. Dhawan, B. N. Mehrotra and C. Ray, “Screening of Indian Plants for Biological Activity: Part 1,” Indian Journal of Experimental Biology, Vol. 6, No. 4, 1968, pp. 232-247. |
[16] | G. Bagalkotkar, S. R. Sagineedu, M. S. Saad and J. Stanslas, “Phytochemicals from Phyllantus niruri L. and Their Pharmacological Properties: A Review,” Journal of Pharmacy and Pharmacology, Vol. 58, No. 12, 2006, pp. 15591570. sdoi:10.1211/jpp.58.12.0001 |
[17] | A. D. Naik and A. R. Juvekar, “Effect of Alkaloidal Extract of Phyllantus niruri on HIV Replication,” Indian Journal of Medical Science, Vol. 57, No. 9, 2003, pp. 387-393. |
[18] | J. L. Nishiura, A. H. Campos, M. A. Boim, I. P. Heilberg and N. Schor, “Phyllantus niruri Normalizes Elevated Urinary Calcium Levels in Calcium Stone Forming (CSF) Patients,” Urological Research, Vol. 32, No. 5, 2004, pp. 362-366. doi:10.1007/s00240-004-0432-8 |
[19] | L. G. Ranilla, Y.-I. Kwon, E. Apostolidis and K. Shetty, “Phenolic Compounds, Antioxidant Activity and in Vitro Inhibitory Potential against Key Enzymes Relevant for Hyperglycemia and Hypertension of Commonly Used Medicinal Plants, Herbs and Spices in Latin America,” Bioresource Technology, Vol. 101, No. 12, 2010, pp. 46764689. doi:10.1016/j.biortech.2010.01.093 |
[20] | S. M. Sabir and J. B. T. Rocha, “Water-Extractable Phytochemicals from Phyllanthus niruri Exhibit Distinct in Vitro Antioxidant and in Vivo Hepatoprotective Activity against Paracetamol-Induced Liver Damage in Mice” Food Chemistry, Vol. 111, No. 4, 2008, pp. 845-851. doi:10.1016/j.foodchem.2008.04.060 |
[21] | L. Taylor, “Technical Data Report for Graviola, Annona Muricata,” Sage Press, Austin, 2002. |
[22] | C. A. Lans, “Ethnomedicines Used in Trinidad and Tobago for Urinary Problems and Diabetes Mellitus,” Journal of Ethnobiology and Ethnomedicine, Vol. 2, No. 52, 2006, pp. 45-55. doi:10.1186/1746-4269-2-45 |
[23] | H. Sulaiman, A. H. Roslida, O. Fezah, K. L. Tan, Y. S. Tor and C. I. Tan, “Chemopreventive Potential of Annona Muricata L. Leaves on Chemically-Induced Skin Papillomagenesis in Mice,” Asian Pacific Journal of Cancer Prevention, Vol. 13, No. 6, 2012, pp. 2533-2539. doi:10.7314/APJCP.2012.13.6.2533 |
[24] | J. G. de Melo, T. A. de Sousa Araújo, V. T. N. de Almeida e Castro, D. L. de Vasconcelos Cabral, M. do Desterro Rodrigues, S. C. do Nascimento, E. L. Cavalcanti de Amorim, U. P. de Albuquerque, “Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil,” Molecules, Vol. 15, No. 12, 2010, pp. 8534-8542. doi:10.3390/molecules15128534 |
[25] | R. Baskar, V. Rajeswari and T. S. Kumar, “In Vitro Antioxidant Studies in Leaves of Annona Species,” Indian Journal of Experimental Biology, Vol. 45, No. 5, 2007, pp. 480-485. |
[26] | K. Sundarrao, I. Burrows and M. Kuduk, “Preliminary Screening of Anti-Bacterial and Anti-Tumor Activities of Papuan New Guinean Active Medicinal Plants,” Pharmaceutical Biology, Vol. 31, No. 1, 1993, pp. 3-6. doi:10.3109/13880209309082909 |
[27] | M. Heinrich, M. Kuhnt and C. W. Wright, “Parasitological and Microbiological Evaluation of Mixe Indian Medicinal Plants (Mexico),” Journal of Ethnopharmacology, Vol. 36, No. 1, 1992, pp. 81-85. doi:10.1016/0378-8741(92)90063-W |
[28] | O. V. de Sousa, G. D. V. Vieira, J. J. R. G. de Pinho et al., “Antinociceptive and Anti-Inflammatory Activities of the Ethanol Extract of annona muricata L. Leaves in Animal Models,” International Journal of Molecular Sciences, Vol. 11, No. 5, 2010, pp. 2067-2078. doi:10.3390/ijms11052067 |
[29] | K. Zurowska, “Amazonian and Andean Phytotherapy,” Tower Press, Gdańsk, 2001. |
[30] | N. Acero, F. Llinares, A. Galán de Mera, B. Oltra and D. Munoz-Mingarro, “Apoptotic and Free Radical Scavenging Properties of the Methanolic Extract of Gentianella alborosea,” Fitoterapia, Vol. 77, No. 8, 2006, pp. 475477. doi:10.1016/j.fitote.2006.05.020 |
[31] | J. Serkedjieva and A. J. Hay, “In Vitro Anti-Influenza Virus Activity of a Plant Preparation from Geranium sanguineum L.,” Antiviral Research, Vol. 37, No. 2, 1998, pp. 221-230. doi:10.1016/S0166-3542(97)00067-3 |
[32] | M. Sokmena, M. Angelova, E. Krumova, S. Pashova, S. Ivancheva, A. Sokmen and J. Serkedjieva, “In Vitro Antioxidant Activity of Polyphenol Extracts with Antiviral Properties from Geranium sanguineum L.,” Life Sciences, Vol. 76, No. 25, 2005, pp. 2981-2993. doi:10.1016/j.lfs.2004.11.020 |
[33] | A. F. Ospina, J. P. C. Guerrero, Y. C. O. Buendía, I. B. P. Bolívar and F. D. Castillo, “Antiinflammatory, Antioxidant and Antibacterial Activity of Two Species of Tabebuia Genus,” Revista Cubana de Plantas Medicinales, Vol. 18, No. 1, 2013, pp. 34-46. |
[34] | R. W. Bussmann and A. Glenn, “Traditional Knowledge for Modern Ailments—Plants Used for the Treatment of Diabetes and Cancer in Northern Peru,” Journal of Medical Plants Research, Vol. 5, No. 31, 2011, pp. 69166930. |
[35] | G. Cioffi, P. Montoro, O. Lock de Ugaz, A. Vassallo, L. Severino, C. Pizza and N. de Tommasi, “Antioxidant Bibenzyl Derivatives from Notholaena Nivea Desv,” Molecules, Vol. 16, No. 3, 2011, pp. 2527-2541. doi:10.3390/molecules16032527 |
[36] | R. W. Bussmann and A. Glenn, “Medicinal Plants Used in Northern Peru for Reproductive Problems and Female Health,” Journal of Ethnobiology and Ethnomedicine, Vol. 6, No. 1, 2010, pp. 30-41. doi:10.1186/1746-4269-6-30 |
[37] | M. P. Kahkonen, A. I. Hopia, H. J. Vuorela, J. P. Rauha, K. Pihlaja, T. S. Kujala and M. Heinonen, “Antioxidant Activity of Plant Extracts Containing Phenolic, Compounds,” Journal of Agricultural and Food Chemistry, Vol. 47, No. 10, 1999, pp. 3954-3962. doi:10.1021/jf990146l |
[38] | D. Sanna, G. Delogu, M. Mulas, M. Schirra and A. Fadda, “Determination of Free Radical Scavenging Activity of Plant Extracts through DPPH Assay: An EPR and UVVis Study,” Food Analytical Methods, Vol. 5, No. 4, 2012, pp. 759-766. doi:10.1007/s12161-011-9306-1 |
[39] | R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans, “Antioxidant Activity Applying an Improved ABTS Radical Cation Decolorization Assay,” Free Radical Biology and Medicine, Vol. 26, No. 9-10, 1999, pp. 1231-1237. doi:10.1016/S0891-5849(98)00315-3 |
[40] | I. F. Benzie and J. J. Strain, “The Ferric Reducing Ability of Plasma (FRAP) as a Measure of ‘Antioxidant Power’: The FRAP Assay,” Analytical Biochemistry, Vol. 239, No. 1, 1996, pp. 70-76. doi:10.1006/abio.1996.0292 |
[41] | V. Singleton, R. Orthofer and R. M. Lamuela-Raventos, “Analysis of Total Phenols and Other Oxidation Substrates and Antioxidants by Means of Folin-Ciocalteu Reagent,” Methods in Enzymology, Vol. 299, No. 39, 1999, pp. 152-175. doi:10.1016/S0076-6879(99)99017-1 |
[42] | I. Ferreira, E. Aires, J. C. M. Barreira and L. Estevinho, “Antiooxidant Activity of Portuguese Honey Samples: Different Contributions of the Entire Honey and Phenolic Extract,” Food Chemistry, Vol. 114, No. 4, 2009, pp. 14381443. doi:10.1016/j.foodchem.2008.11.028 |
[43] | Current Protocols in Food Analytical Chemistry, “Detection and Measurement of Carotenoids by UV/VIS Spectrophotometry,” 2001. |
[44] | R. Pilarski, H. Zielinski, D. Ciesiolka and K. Gulewicz, “Antioxidant Activity of Ethanolic and Aqueous Extracts of Uncaria Tomentosa (Willd.) DC,” Journal of Ethnopharmacology, Vol. 104, No. 1-2, 2006, pp. 18-23. doi:10.1016/j.jep.2005.08.046 |