Wednesday, 9 March 2016

Born on March 5 - March 6

1908Rex Harrison, actor.
My Fair Lady' is turning 50 — and it's a better movie than you remember via @TIMEHistory
1938Lynn Margulis, biologist.
Lynn Margulis (1938-2011)

March 6
1853Giuseppe Verdi’s opera La Traviata premieres in Venice.
1857The Supreme Court’s Dred Scott decision holds that blacks cannot be citizens.

1860While campaigning for the presidency, Abraham Lincoln makes a speech defending the right to strike.

1884Over 100 suffragists, led by Susan B. Anthony, present President Chester A. Arthur with a demand that he voice support for female suffrage.
1888Louisa May Alcott dies just hours after the burial of her father.
1899Aspirin is patented following Felix Hoffman’s discoveries about the properties of acetylsalicylic acid.


[From willow bark to acetylsalicylic acid].

[Article in Danish]


Acetylsalicylic acid is one of the most widely used drugs in the world. Its ancestry the salicylates, including salicin and salicylic acid, are found in the bark and leaves of the willow and poplar trees. The ancient Sumerians and Egyptians, as well as Hippocrates, Celsus, Pliny the Elder, Dioscorides and Galen used these natural products as remedies for pain, fever and inflammation. In the Middle Ages these remedies were used for fever and rheumatism by Hildegard of Bingen and Henrik Harpestreng. The first "clinical trial" was reported by Edward Stone in 1763 with a successful treatment of malarial fever with the willow bark. In 1876 the antirheumatic effect of salicin was described by T. MacLagan, and that of salicylic acid by S. Stricker and L. Riess. Acetylsalicylic acid was synthesized by Charles Gerhardt in 1853 and in 1897 by Felix Hoffmann in the Bayer Company. The beneficial effect of acetylsalicylic acid (Aspirin) on pain and rheumatic fever was recognized by K. Witthauer and J. Wohlgemuth, and the mechanism of action was explained in 1971 by John Vane. Today the antithrombotic effect of acetylsalicylic acid and new aspects of ongoing research demonstrates a still living drug.
Born on March 6
1475Michelangelo Buonarroti, painter, sculptor and architect.
1806Elizabeth Barret Browning, poet (Sonnets from the Portuguese).

Elizabeth Barrett Browning and the Woman Question via @sharethis
1899Richard Leo Simon, publisher, partner of Max Schuster.
1908Lou Costello, American comedian, partner of Bud Abbott.
1928Gabriel Garcia-Marquez, Columbian-born novelist (One Hundred Years of SolitudeLove in the Time of Cholera).
1937Valentina Nikolayeva-Tereshkova, Russian astronaut, the first woman to orbit the Earth.
1944Dame Kiri Te Kanawa, operatic soprano.