Molecules. 2015 Nov 5;20(11):20014-30. doi: 10.3390/molecules201119674.
- 1Institute
of General and Experimental Biology, Siberian Division, Russian Academy
of Science, Sakh'yanovoy Str., 6, Ulan-Ude 670047, Russia. olennikovdn@mail.ru.
- 2Institute
of General and Experimental Biology, Siberian Division, Russian Academy
of Science, Sakh'yanovoy Str., 6, Ulan-Ude 670047, Russia. ninkk@mail.ru.
- 3Department of Biochemistry and Biotechnology, North-Eastern Federal University, 58 Belinsky Str., Yakutsk 677027, Russia. hofnung@mail.ru.
- 4Faculty of the Veterinarian Medicine, Yakut State Agricultural Academy, 15 Krasil'nikova Str., Yakutsk 677007, Russia. nir06@mail.ru.
- 5Faculty of the Veterinarian Medicine, Yakut State Agricultural Academy, 15 Krasil'nikova Str., Yakutsk 677007, Russia. vladimirov.l15@yandex.ru.
Abstract
As a result of the wide distribution of herbal
teas the data on nutritional characterisation, chemical profile and
biological activity of these products are required. The decoctions of
Gentiana algida, G. decumbens, G. macrophylla and G. triflora herb teas
were nutritionally characterized with respect to their macronutrients,
demonstrating the predominance of polysaccharides and low lipid content.
Gentian decoctions were also submitted to a microcolumn RP-HPLC-UV
analysis of phytochemicals demonstrating a high content of iridoids
(177.18-641.04 μg/mL) and flavonoids (89.15-405.71 μg/mL). Additionally,
mangiferin was detected in samples of G. triflora tea (19.89 μg/mL).
Five free sugars (fructose, glucose, sucrose, gentiobiose, gentianose)
were identified in all gentian teas studied, as well as six organic
acids (malic, citric, tartaric, oxalic, succinic, quinic). Pectic
polysaccharides with a high content of rhamnogalacturonans and
arabinogalactans were also identified and characterized in gentian
decoctions for the first time. Gentian tea decoctions and their specific
compounds (gentiopicroside, loganic acid-6'-O-β-d-glucoside,
isoorientin, isoorientin-4'-O-β-d-glucoside, mangiferin, water-soluble
polysaccharides) showed a promising antimicrobial, anti-inflammatory and
antioxidant potentials. Evidences obtained indicate the prospective use
of gentian herb teas as food products and medicines.
KEYWORDS:
Gentiana
algida; Gentiana decumbens; Gentiana macrophylla; Gentiana triflora;
anti-inflammatory; antimicrobial activity; antioxidant; flavonoids;
iridoids; polysaccharide
