Thursday, 24 August 2017

Arnica montana L. – a plant of healing: review

Journal of Pharmacy and Pharmacology Volume 69, Issue 8, 1 August 2017, Pages 925-945 Kriplani, P.abEmail Author, Guarve, K.a, Baghael, U.S.c View Correspondence (jump link) aGuru Gobind Singh College of Pharmacy, Yamunanagar, Haryana, India bI.K. Gujral Punjab Technical University, Jalandhar, Punjab, India cDepartment of Pharmaceutical Sciences, Khalsa College, Amritsar, Punjab, India Abstract View references (90) Objectives: Arnica montana is a widely used therapeutic plant used traditionally to treat various ailments. The objective of this study was to evaluate the botany, phytochemistry and ethnopharmacology along with special emphasis given on pharmacological activity of plant A. montana. Key findings: The plant extracts have been reported to possess antibacterial, antitumor, antioxidant, anti-inflammatory, antifungal and immunomodulatory activity. A wide range of chemical compounds including sesquiterpene lactones and their short-chain carbonic acid esters, flavonoids, carotenoids, essential oils, diterpenes, arnidiol, pyrrolizidine alkaloids, coumarins, phenolic acids, lignans and oligosaccharides, etc., are found in different parts of the plant. Summary: It has been scrutinized that extensive research has been carried out to explore the therapeutic potential of flowers of the plant. Therefore, investigations should be carried out to explore the therapeutic potential of other parts of the plant for better therapeutic utilization. © 2017 Royal Pharmaceutical Society Author keywords anti-inflammatory Arnica montana helenalin sesquiterpene lactones Indexed keywords EMTREE drug terms: Arnica montana extractcarotenoidcoumarinditerpeneessential oilesterflavonoidlignanoligosaccharidephenolpyrrolizidine alkaloidsesquiterpene lactoneterpenethymol EMTREE medical terms: analgesic activityantibacterial activityanticoagulationantifungal activityantihair loss activityantiinflammatory activityantimicrobial activityantineoplastic activityantiosteoarthritic activityantiosteoporotic activityantioxidant activityantiplatelet activityArnica montanabiological activitybotanybreathing patterncirculationcoughingdrug activitydrug mechanismethnopharmacologyflowerhair growthhumanhypopigmentationhypopigmentation activityimmunomodulationinotropisminsecticidal activityliver protectionnonhumanossificationphytochemistryplant rootplant seedReviewtherapeutic researchtoxicologyureotonic activity Chemicals and CAS Registry Numbers: coumarin, 91-64-5; phenol, 108-95-2, 3229-70-7; thymol, 89-83-8 ISSN: 00223573 CODEN: JPPMA Source Type: Journal Original language: English DOI: 10.1111/jphp.12724 Document Type: Review Publisher: Blackwell Publishing Ltd References (90) View in search results format All Export Print E-mail Save to PDF Create bibliography View all 90 references 1 Sahid, M., Rao, N.K. 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