Successful Pregnancy after Treatment with Chinese Herbal Medicine in a 43-Year-Old Woman with Diminished Ovarian Reserve and Multiple Uterus Fibrosis: A Case Report.

Medicines (Basel). 2017 Feb 9;4(1). pii: E7. doi: 10.3390/medicines4010007. Teng B1,2, Peng J3,4, Ong M5, Qu X6. Author information 1 School of Life Sciences, University of Technology Sydney, NSW 2007, Australia. tengbq@mail.sysu.edu.cn. 2 Department of Obstetrics, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Guangzhou 510630, China. tengbq@mail.sysu.edu.cn. 3 School of Life Sciences, University of Technology Sydney, NSW 2007, Australia. PengJie528@outlook.com. 4 Department of Gynaecology and Obstetrics, Suzhou Wuzhong People's Hospital, Suzhou 215128, China. PengJie528@outlook.com. 5 School of Life Sciences, University of Technology Sydney, NSW 2007, Australia. Madeleine.L.Ong@student.uts.edu.au. 6 School of Life Sciences, University of Technology Sydney, NSW 2007, Australia. Xianqin.Qu@uts.edu.au. Abstract OBJECTIVE: To highlight a natural approach to coexisting oligomenorrhea, subfertility, luteal phase insufficiency and multiple fibroids cohesively when in vitro fertilisation (IVF) has failed. CASE PRESENTATION: A 43-year-old woman with diminished ovarian reserve and multiple uterine fibroids had previously been advised to discontinue IVF treatment. According to Chinese Medicine diagnosis, herbal formulae were prescribed for improving age-related ovarian insufficiency as well as to control the growth of fibroids. After 4 months of treatment, the patient's menstrual cycle became regula r and plasma progesterone one week after ovulation increased from 10.9 nmol/L to 44.9 nmol/L. After 6 months, she achieved a natural conception, resulting in a live birth of a healthy infant at an estimated gestational age of 40 weeks. CONCLUSIONS: The successful treatment with Chinese Herbal Medicine for this case highlights a natural therapy to manage infertility due to ovarian insufficiency and multiple fibroids after unsuccessful IVF outcome. KEYWORDS: Chinese herbal medicine; uterus fibrosis; diminished ovarian reserve; infertility; in vitro fertilization PMID: 28930223 PMCID: PMC5597078 DOI: 10.3390/medicines4010007 Free PMC Article