Botanical Adulterants Program Releases New Bulletin on Substitution of Rhodiola rosea with Other Rhodiola Species

ABC ADVISORY New bulletin details authenticity issues in the rhodiola trade AUSTIN, Texas (October 16, 2017) — The ABC-AHP-NCNPR Botanical Adulterants Program announces the publication of a new Botanical Adulterants Bulletin (BAB) on Rhodiola rosea. The rhizome and roots of rhodiola have been used for a number of ailments in traditional herbal medicine, particularly in northern Europe. Modern scientific research on R. rosea began in the 1960s in Russia and established its use as an adaptogen. Much of the rhodiola material in trade currently comes from China, where it was introduced through Western research. Rhodiola rosea was never part of the traditional Chinese medicine (TCM) system, and is not considered to be the primary or authentic species in China. Rather, it is one of several species of Rhodiola (of which R. crenulata seems to be the most abundant in commerce) collectively known as hong jing tian. As such, it may not be surprising that analyses of materials sold in China as “R. rosea” have been found to contain other Rhodiola species, especially R. crenulata and R. serrata. The bulletin was co-authored by Ezra Bejar, PhD, John Cardellina II, PhD, and Roy Upton. A total of 19 experts with knowledge of the rhodiola supply chain or expertise in medicinal plants, analytical chemistry, and related scientific disciplines reviewed the document. The rhodiola bulletin includes information about the production and market importance of rhodiola, its main medicinal uses, a list of the known adulterants and substituted species, substitution frequency, and analytical methods to distinguish R. rosea from closely related species. “This is one of the cases in which the commercial market was established on a particular species, in this case Rhodiola rosea, but numerous other closely related species were similarly used in various herbal traditions,” said Upton, the executive director of the American Herbal Pharmacopoeia (AHP). “Are alternate species adulterants, substitutions, or are they legitimately used interchangeably? This comes down to the specific action desired, the ingredient specification, and label claim.” Stefan Gafner, PhD, chief science officer of the American Botanical Council (ABC) and technical director of Botanical Adulterants Program, noted: “The understanding of what ‘rhodiola’ means apparently differs among Western manufacturers of herbal dietary supplements and the Chinese suppliers who sell rhodiola root and rhizome, and extracts thereof. This has led to a situation in which a number of Rhodiola species are found in the supply chain.” “If a dietary supplement product label lists Rhodiola rosea as an ingredient, it is important for manufacturers to set appropriate specifications for ingredient identity and to communicate these clearly to the suppliers,” Gafner continued. “In addition, suitable analytical test methods that are able to distinguish among Rhodiola rosea and other Rhodiola species must be in place.” The goal of the bulletins is to summarize topics regarding botanical identity and adulteration, thus allowing quality control personnel and lab technicians in the herbal medicine, botanical ingredient, dietary supplement, cosmetic, conventional food, and other industries in which botanical ingredients are used to be aware of adulteration problems that are apparently widespread and may imply health/safety concerns. The rhodiola bulletin is the 11th publication in the series of BABs compiled by the Botanical Adulterants Program. In August 2017, the program released a bulletin on the adulteration of tea tree oil (Melaleuca alternifolia) with undisclosed lower-cost materials, including synthetic chemicals. The bulletins and all other program publications are freely accessible to all ABC members, registered users of the ABC website, and all members of the public on the program’s website (registration required). About the ABC-AHP-NCNPR Botanical Adulterants Program The ABC-AHP-National Center for Natural Products Research (NCNPR) Botanical Adulterants Program is an international consortium of nonprofit professional organizations, analytical laboratories, research centers, industry trade associations, industry members, and other parties with interest in herbs and medicinal plants. The program advises industry, researchers, health professionals, government agencies, the media, and the public about the various challenges related to adulterated botanical ingredients sold in commerce. To date, more than 190 US and international parties have financially supported or otherwise endorsed the program. So far, the program has published 34 extensively peer-reviewed articles, BABs, Laboratory Guidance Documents, and Botanical Adulterants Monitor e-newsletters, all of which are available for free to registered users on the program’s website.