Antibacterial activity of five Peruvian medicinal plants againstPseudomonas aeruginosa

Open Access funded by Hainan Medical University

Under a Creative Commons license

doi:10.1016/j.apjtb.2015.07.016

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Abstract

Objective

To evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extracts obtained from five different Peruvian medicinal plants.

Methods

The plants were chopped and soaked in absolute ethanol (1:2, w/v). The antibacterial activity of compounds against P. aeruginosa was evaluated using the cup-plate agar diffusion method.

Results

The extracts from Maytenus macrocarpa (“Chuchuhuasi”), Dracontium loretense Krause (“Jergon Sacha”), Tabebuia impetiginosa (“Tahuari”), Eucalyptus camaldulensis Dehn (eucalyptus), Uncaria tomentosa (“Uña de gato”) exhibited favorable antibacterial activity against P. aeruginosa. The inhibitory effect of the extracts on the strains of P. aeruginosatested demonstrated that Tabebuia impetiginosa and Maytenus macrocarpa possess higher antibacterial activity.

Conclusions

The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.

Keywords

Pseudomonas;
Medicinal plants;
Maytenus macrocarpa;
Dracontium loretense Krause;
Tabebuia impetiginosa;
Eucalyptus;
Uncaria tomentosa

Peer review under responsibility of Hainan Medical University.

: Corresponding author. Universidad Peruana de Ciencias Aplicadas, Avenue San Marcos cdra, Cedros de Villa, Lima, Perú. Tel.: +51 13133333. Annex 2704; fax: +51 13496025.

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Monday, 24 August 2015