Języki publikacji
Abstrakty
Human
scabies is caused by an infection of the skin by the human itch mite
(Sarcoptes scabiei var. hominis). There are different medications for
the treatment of scabies. This study aimed at comparing the efficacy and
safety of oral ivermectin vs. sulfur 10% ointment for the treatment of
scabies. In total, 420 patients with scabies were enrolled, and
randomized into two groups: the first group received a single dose of
oral ivermectin 200 μg/kg body weight, and the second group received
sulfur 10% ointment and were told to apply this for three successive
days. Treatment was evaluated at intervals of 2 and 4 weeks, and if
there was treatment failure at the 2-week follow-up, treatment was
repeated. A single dose of ivermectin provided a cure rate of 61.9% at
the 2-week follow-up, which increased to 78.5% at the 4-week follow-up
after repeating the treatment. Treatment with single applications of
sulfur 10% ointment was effective in 45.2% of patients at the 2-week
follow-up, which increased to 59.5% at the 4-week follow-up after this
treatment was repeated. A single dose of ivermectin was as effective as
single applications of sulfur 10% ointment at the 2-week follow-up.
After repeating the treatment, ivermectin was superior to sulfur 10%
ointment at the 4-week follow up. The delay in clinical response with
ivermectin suggests that it may not be effective against all the stages
in the life cycle of the parasite.
Twórcy
autor
- Tabriz University of Medical Sciences, Aras Branch, Tabriz, Iran
autor
- Young Researchers and Elite Club, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran
Bibliografia
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Identyfikator YADDA
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