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Monday 21 September 2015

Preventive use of Bach flower Rescue Remedy in the control of risk factors for cardiovascular disease in rats


Summary

Objectives

To evaluate the effect of Bach flower Rescue Remedy on the control of risk factors for cardiovascular disease in rats.

Design

A randomized longitudinal experimental study.

Methods

Eighteen Wistar rats were randomly divided into three groups of six animals each and orogastrically dosed with either 200 μl of water (group A, control), or 100 μl of water and 100 μl of Bach flower remedy (group B), or 200 μl of Bach flower remedy (group C) every 2 days, for 20 days. All animals were fed standard rat chow and water ad libitum.

Main outcome measures

Urine volume, body weight, feces weight, and food intake were measured every 2 days. On day 20, tests of glycemia, hyperuricemia, triglycerides, high-density lipoprotein (HDL) cholesterol, and total cholesterol were performed, and the anatomy and histopathology of the heart, liver and kidneys were evaluated. Data were analyzed using Tukey's test at a significance level of 5%.

Results

No significant differences were found in food intake, feces weight, urine volume and uric acid levels between groups. Group C had a significantly lower body weight gain than group A and lower glycemia compared with groups A and B. Groups B and C had significantly higher HDL-cholesterol and lower triglycerides than controls. Animals had mild hepatic steatosis, but no cardiac or renal damage was observed in the three groups.

Conclusion

Bach flower Rescue Remedy was effective in controlling glycemia, triglycerides, and HDL-cholesterol and may serve as a strategy for reducing risk factors for cardiovascular disease in rats. This study provides some preliminary “proof of concept” data that Bach Rescue Remedy may exert some biological effects.

Keywords

  • Wistar rats;
  • Bach flowers;
  • Preventive medicine;
  • Animal experimentation;
  • Complementary therapies

Corresponding author at: Rua Marília Viana de Andrade 77, Bairro Fátima I, CEP 37550-000 Pouso Alegre, MG, Brazil. Tel.: +55 35 3423 4230; fax: +55 35 3422 9200.