Volume 102, October 2015, Pages 242–246
Highlights
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- This finding provided evidence for prevalence of staphylococcal bovine mastitis.
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- Rhodomyrtus tomentosa extract possessed high antibacterial potency against staphylococci.
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- The extract showed anti-protein denaturation activity and HRBC stabilization.
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- The extract could be used to reduce inflammatory injury due to bacterial infection.
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- The extract could be applied as an alternative agent against bovine mastitis.
Abstract
Antibiotic
residues in dairy products as well as emergence of antimicrobial
resistance in foodborne pathogens have been recognized as global public
health concerns. The present work was aimed to study a potent
antibacterial extract from natural product as an alternative treatment
for staphylococcal bovine mastitis. Staphylococcal isolates (n = 44)
were isolated from milk samples freshly squeezed from individual cows.
All staphylococcal isolates were resistant to ampicillin, ciprofloxacin,
erythromycin, gentamicin, penicillin, except vancomycin. Rhodomyrtus tomentosa
leaf ethanolic extract was accessed for its antibacterial activity and
anti-inflammatory potential. The extract exhibited profound
antibacterial activity against all of staphylococcal isolates with MIC
and MBC values ranged from 16–64 μg/ml and 64–> 128 μg/ml,
respectively. Moreover, the extract also exerted anti-protein
denaturation and human red blood cell membrane stabilizing activity. The
results support the use of R. tomentosa extract that could be applied to cure bovine mastitis and to reduce inflammatory injury caused by the bacterial infections.
Keywords
- Antibacterial agent;
- Anti-inflammatory;
- Bovine mastitis;
- Rhodomyrtus tomentosa;
- Staphylococcus aureus
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