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Sunday 21 February 2016

A review of the ethnomedicinal uses, phytochemistry and pharmacology of the Pleiocarpa genus

4 January 2016, Pages 1-19


Department of Chemistry, University of the Western Cape, P/Bag x17, Bellville, South Africa
Department of Chemistry and Polymer Science, University of Stellenbosch, P/Bag X1, Matieland, South Africa

Abstract

Pleiocarpa genus is a flowering plant from the Apocynaceae family which are rich sources of phytochemicals and have been reported to be useful in the treatment of gastrointestinal ailments, fever, malaria, pain, diabetes and cancer. The aim of this review is to present the past and current ethnomedicinal uses, phytochemistry and the pharmacology of Pleiocarpa genus which are underexploited as revealed through this review in order to enhance its potential source of phytochemical leads in medicine. Some pharmacological activities of these plants based on their acclaimed ethnomedicinal uses have been investigated by various researchers. The chemical profile of the genus is limited to alkaloids and triterpenoids, where indole alkaloids may be considered as important taxonomical markers. © 2016 Springer Science+Business Media Dordrecht

Author keywords

Apocynaceae; Ethnomedicine; Pharmacology; Phytochemistry; Pleiocarpa mutica; Pleiocarpa pycnantha
ISSN: 15687767 CODEN: PRHEBSource Type: Journal Original language: English
DOI: 10.1007/s11101-015-9449-6Document Type: Article in Press
Publisher: Springer Netherlands
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  Omoyeni, O.A.; Department of Chemistry, University of the Western Cape, P/Bag x17, South Africa; email:nikxyglo@yahoo.com
© Copyright 2016 Elsevier B.V., All rights reserved.