Extracts and essentialoils
from plants are important natural sources of pesticides. These
compounds are considered an alternative to control ectoparasites of
veterinary importance. Schinusmolle, an endemic species of Brazil, produces a high level of essential oil and several other compounds. The aim of this work was to determinate the chemical composition of extracts and essentialoils of S. molle and further to evaluate the activity against eggs and adults of Ctenocephalidesfelisfelis, a predominant flea that infests dogs and cats in Brazil. In an in vitro assay, the non-polar (n-hexane) extract showed 100% efficacy (800 µg cm-2; LD50 = 524·80 µg cm-2) at 24 and 48 h. Its major compound was lupenone (50·25%). Essentialoils from fruits and leaves were evaluated, and had 100% efficacyagainst
adult fleas at 800 µg cm-2 (LD50 = 353·95 µg cm-2) and at 50 µg cm-2
(LD50 = 12·02 µg cm-2), respectively. On the other hand, the essential oil from fruits and leaves was not active against flea eggs. This is the first study that reports the insecticidal effects of essentialoils and extracts obtained from SchinusmolleagainstCtenocephalidesfelisfelis.