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Monday, 19 December 2016

moringa

Emma Hardie Moringa Cleansing Balm


Moringa Cleansing BalmMoringa seed extract, Wild Sea Fennel and Vitamin E: Balance, purify and help to minimise the appearance of open pores. Orange, Neroli and Mandarin extracts: Rejuvenate and revitalise the skin. Jasmine, Cedarwood and Rose: Help to recondition dull, dry, dehydrated and mature skins



2016 Feb 8;5(1):1-6. doi: 10.5455/jice.20160201055629.

Wound healing properties of ethyl acetate fraction of Moringa oleifera in normal human dermal fibroblasts.

Author information

  • 1Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
  • 2Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

Abstract

BACKGROUND/AIM:

Wounds are the outcome of injuries to the skin that interrupt the soft tissue. Healing of a wound is a complex and long-drawn-out process of tissue repair and remodeling in response to injury. A large number of plants are used by folklore traditions for the treatment of cuts, wounds and burns. Moringa oleifera (MO) is an herb used as a traditional folk medicine for the treatment of various skin wounds and associated diseases. The underlying mechanisms of wound healing activity of ethyl acetate fraction of MO leaves extract are completely unknown.

MATERIALS AND METHODS:

In the current study, ethyl acetate fraction of MO leaves was investigated for its efficacy on cell viability, proliferation and migration (wound closure rate) in human normal dermal fibroblast cells.

RESULTS:

Results revealed that lower concentration (12.5 µg/ml, 25 µg/ml, and 50 µg/ml) of ethyl acetate fraction of MO leaves showed remarkable proliferative and migratory effect on normal human dermal fibroblasts.

CONCLUSION:

This study suggested that ethyl acetate fraction of MO leaves might be a potential therapeutic agent for skin wound healing by promoting fibroblast proliferation and migration through increasing the wound closure rate corroborating its traditional use.

KEYWORDS:

Active fractions; cell proliferation; migration; natural products; scratch assay