- 1
- Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta,
 5S131 Lois Hole Hospital for Women, Robbins Pavilion, Royal Alexandra 
Hospital, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3 V9, Canada. 
jcroden@ualberta.ca.
- 2
- Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta,
 5S131 Lois Hole Hospital for Women, Robbins Pavilion, Royal Alexandra 
Hospital, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3 V9, Canada. 
sue.ross@albertahealthservices.ca.
- 3
- Faculty of Pharmacy
 and Pharmaceutical Sciences, 3-171 Edmonton Clinic Health Academy, 
11405 - 87 Avenue NW, Edmonton, AB, T6G 1C9, Canada. 
nese.yuksel@ualberta.ca.
- 4
- Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta,
 5S131 Lois Hole Hospital for Women, Robbins Pavilion, Royal Alexandra 
Hospital, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3 V9, Canada. 
bsydora@ualberta.ca.
 
 
Abstract
BACKGROUND: 
Menopause
 is a natural phase in a woman's aging process, characterized by the 
cessation of menstruation. Women who are going through the menopause 
transition can experience physiological symptoms that significantly 
impact their quality of life. Concern about adverse effects of 
traditional hormone therapy often leads women to purchase 
over-the-counter (OTC) natural health products (NHPs). The goal of this 
study was toinvestigate the range of OTC NHPs for menopause available to
 Canadian women, and the packaging information they can access to make 
self-management decisions.
METHODS: 
Edmonton
 stores belonging to each of nine Canadian pharmacy chains were visited 
to identify NHPs marketed for the relief of menopausal symptoms. Details
 were extracted from the packaging: a) product name and manufacturer, b)
 Health Canada license number, c) medically active ingredients, d) 
claims of efficacy, e) contra-indications and warnings, and f) daily 
cost. Data were entered and analyzed using Microsoft Excel.
RESULTS: 
We
 identified 20 OTC NHP menopausal products, 19 of which had Health 
Canada license numbers. Twenty-eight medically active ingredients were 
identified, with the most common being black cohosh (in 14 products) and
 soy isoflavones (n = 7), chaste tree (n = 5), and dong quai (n = 3). 
Most products claimed they would relieve vasomotor symptoms, including 
hot flashes (n = 14) and night sweats (n = 10). Each product had a 
labeled contraindication for at least one specific condition. Costs per 
recommended daily dose ranged from $0.07 to a maximum of $2.50 (CAD$).
CONCLUSION: 
Natural
 health products for menopausal symptoms are easily available to 
Canadian women. The lack of clear evidence of product efficacy makes the
 need for easily accessible, balanced information on this topic 
important for women to make well informed choices.