Antioxidant Properties of the Artist's Conk Medicinal Mushroom, Ganoderma applanatum (Agaricomycetes), upon Cultivation with para-Substituted Phenolic Compounds and Tea Leaf Extracts

Int J Med Mushrooms. 2018;20(6):549-560. doi: 10.1615/IntJMedMushrooms.2018026329. Tsivileva O1, Pankratov A2, Misin V3, Zavyalov A3, Volkov V3, Tsymbal O2, Yurasov N2, Nikitina VE1. Author information 1 Laboratory of Microbiology, Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia. 2 Institute of Chemistry, National Research Saratov State University, Saratov, Russia. 3 Laboratory of Antioxidants, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia. Abstract In this study we elucidate antioxidative properties of the mushroom Ganoderma applanatum (Pers.) Pat. enhanced by submerged culture with para-hydroxyphenolic compounds and tea leaf extracts. The tea extract has been shown to increase to different extents the antioxidative efficiency of para-substituted phenolics, with the most profound effect for 2-(4-hydroxyphenyl)ethane-1-ol (tyrosol). Within the range of physiological concentrations, the symbatic correlation of the antioxidative action of the fungal samples with the volume of tea extract in the submerged culture medium was observed. We propose an approach to obtain, through the use of black tea extracts as the nutrient medium component, large amounts of G. applanatum seeding mycelia; the extract exerts a profound positive effect on the level of phenolic-type antioxidants. PMID: 29953351 DOI: 10.1615/IntJMedMushrooms.2018026329