Mechanism of Action of Anticancer Herbal Medicines

January 2018 DOI: 10.1007/978-981-10-8417-1_14 In book: Anticancer Plants: Mechanisms and Molecular Interactions Mohd GulfishanMohd GulfishanMuhammad AfzalImran Kazmi Ajmat Jahan © 2018 Anticancer Plants: Mechanisms and Molecular Interactions Volume 4 Editors: Akhtar, Mohd Sayeed, Swamy, Mallappa Kumara (Eds.) Describes the basis of isolated bioactive anticancer compounds from anticancer plants About the authors This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research. Table of contents (14 chapters) Omics: A Holistic Approach in Cancer Treatment Bora, Madhumati (et al.) Pages 1-26 Preview Plant miRNAs and Phytomolecules As Anticancer Therapeutics Shukla, Nikita (et al.) Pages 27-41 Potential of Herbal Medicines in Colorectal Carcinoma and Their Mechanism of Action Panneerselvan, Navina (et al.) Pages 43-97 Elucidation of Mechanisms of Anticancer Plant Compounds Against the Tumor Cells Narayanaswamy, Radhakrishnan (et al.) Pages 99-130 Computational Approach Towards Exploring Interaction of Target Protein-Phytocompounds in Drug Development for Breast Cancer Elengoe, Asita (et al.) Pages 131-141 Anticancer Potential of Andrographolide, a Diterpenoid Lactone from Andrographis paniculata: A Nature’s Treasure for Chemoprevention and Therapeutics Khan, Imran (et al.) Pages 143-163 Anticancer Activity of Herbal Medicine: Mechanism of Action Singh, Nand Kumar (et al.) Pages 165-196 Metabolomic Study of Chemo-preventive Phytochemicals and Their Therapeutic Prospects Parasar, Nibir Ranjan (et al.) Pages 197-207 CADD Studies Applied to Secondary Metabolites in the Anticancer Drug Research Scotti, Luciana (et al.) Pages 209-225 Anticancerous Plant Compounds Affecting the Power House of Cancerous Cells: A Possible Herbal Mitocan Mani, Shalini (et al.) Pages 227-258 Phytoestrogens as a Natural Source for the Possible Colon Cancer Treatment Challa, Suresh (et al.) Pages 259-281 Bioinformatics Approaches for Genomics and Post Genomics Applications of Anticancer Plants Mehta, Avni (et al.) Pages 283-317 Fruits of Rosaceae Family as a Source of Anticancer Compounds and Molecular Innovations Sameeullah, Muhammad (et al.) Pages 319-336 Mechanism of Action of Anticancer Herbal Medicines Gulfishan, Mohd (et al.) Pages 337-360 Read this book on SpringerLink Buy this book eBook 130,89 € price for Spain (gross) Buy eBook ISBN 978-981-10-8417-1 Digitally watermarked, DRM-free Included format: PDF, EPUB ebooks can be used on all reading devices Immediate eBook download after purchase Hardcover 166,39 € FAQ Policy Services for this Book Download Product Flyer Reserve an Online Book Review Copy Download High-Resolution Cover