Tagetes spp. Essential Oils and Other Extracts: Chemical Characterization and Biological Activity.

Molecules. 2018 Nov 1;23(11). pii: E2847. doi: 10.3390/molecules23112847. Salehi B1,2, Valussi M3, Morais-Braga MFB4, Carneiro JNP5, Leal ALAB6, Coutinho HDM7, Vitalini S8, Kręgiel D9, Antolak H10, Sharifi-Rad M11, Silva NCC12, Yousaf Z13, Martorell M14, Iriti M15, Carradori S16, Sharifi-Rad J17,18. Author information 1 Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran 88777539, Iran. bahar.salehi007@gmail.com. 2 Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 22439789, Iran. bahar.salehi007@gmail.com. 3 European Herbal and Traditional Medicine Practitioners Association (EHTPA), 25 Lincoln Close, Tewkesbury GL20 5TY, UK. marco.officinalessinia@gmail.com. 4 Laboratory of Microbiology and Molecular Biology-LMBM, Regional University of Cariri-URCA, Crato, CE 63105-000, Brazil. flavianamoraisb@yahoo.com.br. 5 Laboratory of Microbiology and Molecular Biology-LMBM, Regional University of Cariri-URCA, Crato, CE 63105-000, Brazil. nalyda_05@hotmail.com. 6 Laboratory of Microbiology and Molecular Biology-LMBM, Regional University of Cariri-URCA, Crato, CE 63105-000, Brazil. antoniolinkoln@hotmail.com. 7 Laboratory of Microbiology and Molecular Biology-LMBM, Regional University of Cariri-URCA, Crato, CE 63105-000, Brazil. hdmcoutinho@gmail.com. 8 Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy. sara.vitalini@unimi.it. 9 Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Wolczanska 171/173, 90-924 Lodz, Poland. dorota.kregiel@p.lodz.pl. 10 Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Wolczanska 171/173, 90-924 Lodz, Poland. hubert.antolak@gmail.com. 11 Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663335, Iran. mehdi_sharifirad@yahoo.com. 12 Department of Food Science, Faculty of Food Engineering (FEA), University of Campinas (UNICAMP), Campinas 13083-862, Sao Paulo, Brazil. ncirone@unicamp.br. 13 Department of Botany, Lahore College for Women University, Jail Road, Lahore 54000, Pakistan. mussabuswaeshal@hotmail.com. 14 Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion 4070386, VIII-Bio Bio Region, Chile. mmartorell@udec.cl. 15 Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy. marcello.iriti@unimi.it. 16 Department of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. simone.carradori@unich.it. 17 Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 11369, Iran. javad.sharifirad@gmail.com. 18 Department of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, MB R3B 2G3, Canada. javad.sharifirad@gmail.com. Abstract Tagetes (marigold) is native to America, and its cultivation currently extends to other countries in Africa, Asia, and Europe. Many species of this genus, such as T. minuta, T. erecta, T. patula, and T. tenuifolia, are cultivated as ornamental plants and studied for their medicinal properties on the basis of their use in folk medicine. Different parts of the Tagetes species are used as remedies to treat various health problems, including dental, stomach, intestinal, emotional, and nervous disorders, as well as muscular pain, across the world. Furthermore, these plants are studied in the field of agriculture for their fungicidal, bactericidal, and insecticidal activities. The phytochemical composition of the extracts of different Tagetes species parts are reported in this work. These compounds exhibit antioxidant, antiinflammatory, and enzyme inhibitory properties. Cultivation and the factors affecting the chemical composition of Tagetes species are also covered. In the current work, available literature on Tagetes species in traditional medicine, their application as a food preservative, and their antimicrobial activities are reviewed. KEYWORDS: Asteraceae; Tagetes erecta; Tagetes lucida; Tagetes minuta; Tagetes patula; antimicrobial; ethnopharmacology PMID: 30388858 DOI: 10.3390/molecules23112847 Free full text