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Saturday, 13 June 2015

Use of Chinese medicine correlates negatively with the consumption of conventional medicine and medical cost in patients with uterine fibroids: a population-based retrospective cohort study in Taiwan

Research article


Shan-Yu Su12*, Chih-Hsin Muo34 and Donald E Morisky5
1 Department of Chinese Medicine, China Medical University Hospital, No. 2 Yude road, Taichung 40447, Taiwan
2 School of Post-baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
3 College of Medicine, China Medical University, Taichung 40402, Taiwan
4 Management Office for Health Data, China Medical University Hospital, Taichung 40402, Taiwan
5 Department of Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles 90095-1772, CA, USA
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BMC Complementary and Alternative Medicine 2015, 15:129  doi:10.1186/s12906-015-0645-0
The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1472-6882/15/129

Received:28 October 2014
Accepted:13 April 2015
Published:23 April 2015
© 2015 Su et al.; licensee BioMed Central.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Abstract

Background

Chinese medicine is commonly used and covered by health insurance to treat symptoms of uterine fibroids in Taiwan. This retrospective cohort study compared the consumption of conventional western medicine and medical cost between Chinese medicine (CM) users and nonusers among patients with uterine fibroids.

Methods

We extracted 44,122 patients diagnosed with uterine fibrosis between 1996 and 2010 from the National Health Insurance reimbursement database, which is a population-based database released by a government-run health insurance system. Multivariate linear regression models were used to find association between using Chinese medicine and the consumption of conventional medicine, and between using Chinese medicine and medical cost.

Results

The total fibroid-related conventional western medicine consumed by CM users was less than that by nonusers (β = -10.49, P < 0.0001). Three categories of conventional medicines, including antianemics (-3.50 days/year/patient, P < 0.0001), hemostatics (- 1.89 days/year/patient, P < 0.0001), and hormone-related agents (-3.13 days/year/patient, P < 0.0001), were used less in patients who were CM users. Moreover, although using CM increased 16.9 USD per patient in CM users annually (P < 0.0001), the total annual medical cost for treating fibroid was 5610 USD less in CM users than in nonusers (P < 0.0001).

Conclusions

Our results suggested that CM reduced the consumption of conventional medicine, and might be a potential therapeutic substitute for conventional western medicines to treat uterine fibroids with low cost.
Keywords:
Uterine fibroid; Chinese medicine; Conventional western medicine; Iron-deficiency anemia; Hypermenorrhea; Dysmenorrhea