Erythropoietic Effects of Eremomastax polysperma Leaf Extracts on Female Prepubertal and Pubertal Wistar Rats
AUTHOR(S)
PUB. DATE
August 2014
SOURCE
British Journal of Pharmaceutical Research;2014, Vol. 4 Issue 15, p1833
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This study assessed the
erythropoietic effect of Eremomastax polysperma leaf extracts in female
albino Wistar rats. Method: Twenty eight (28) female rats were divided
into two major groups based on their weight and age. The duration of
administration of E. polysperma extracts lasted for twenty one (21)
days. This study was carried out in the Department of Biochemistry
University of Calabar, between February and March 2013. A significant
increase (P<0.05) in red blood cell count (RBC) (8.17±0.48,
6.46±0.37) and Haemoglobin (Hb) count (15.13±1.03, 13.27±0.7) was
observed in the prepubertal group compared to the control, while packed
cell volume (PCV) was significantly increased (P<0.05) in the
pubertal group compared to the control (55.40±4.40, 48.63±2.33
respectively). This suggests that E. polysperma leaf extract can be used
as a haematinic and a therapy for anaemic conditions.
