Anim Sci J. 2015 Oct;86(10):869-77. doi: 10.1111/asj.12370. Epub 2015 Jul 24.
- 1Reseach
and Development Center of Feed & Livestock Development Division,
Nippon Formula Feed Manufacturing Company Limited, Tochigi, Japan.
- 2Department
of Animal Production Science United Graduate School of Agricultural
Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
- 3University Farm, Department of Agriculture, Utsunomiya University, Tochigi, Japan.
Abstract
Solanum glaucophyllum
(SG) contains 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) glycosides. We
investigated the effect of SG on hypocalcemia in cows. Serum levels of
1,25-(OH)2D3, total calcium and phosphorus dose-relatedly increased
after feeding with SG, while serum magnesium and chloride levels fell
(P < 0.05). We also performed an ethylenediaminetetraacetic acid
(EDTA) infusion to induce artificial hypocalcemia. Cows that had been
fed 4.0 mg/kg body weight of SG daily for 2 weeks had a higher serum
concentration of total calcium at the end of EDTA infusion than those
not fed SG (P < 0.05). In a field trial, multiparous cows were
assigned to one of four groups: (1) no SG, (2) 1.3 g or (3) 2.6 g of SG
daily from 14 days before the estimated calving day until 3 days after
calving, or (4) a single feed of 35.75 g SG at 3 days before the
estimated calving day. The concentrations of serum total calcium after
the calving in each treatment group were (1) 7.4, (2) 7.9, (3) 8.0 and
(4) 8.9 mg/dL and higher for (4) than for (1) (P < 0.05). The data
suggests that feeding a high dose of SG before the calving may maintain
higher concentrations of serum calcium after the calving.
© 2015 Japanese Society of Animal Science.
KEYWORDS:
1; 25dihydroxyvitaminD3; Holstein cows; Solanum glaucophyllum; calcium; milk fever
