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Thursday, 12 January 2017

Cardiovascular Consequences of Binge Drinking: An Integrative Review with Implications for Advocacy, Policy, and Research.

2017 Jan 9. doi: 10.1111/acer.13329. [Epub ahead of print]


Author information

  • 1Department of Biobehavioral Health Science, University of Illinois at Chicago, Chicago, Illinois.
  • 2Department of Physical Therapy, , University of Illinois at Chicago, Chicago, Illinois.
  • 3Department of Physical Therapy, Federal University of São Carlos, São Carlos, São Paulo, Brazil.

Abstract

Worldwide, binge drinking is a major public health problem. The popularized health risks associated with binge drinking include physical injury and motor vehicle crashes; less attention has been given to the negative effects on the cardiovascular (CV) system. The primary aims of this review were to provide a summary of the adverse effects of binge drinking on the risk and development of CV disease and to review potential pathophysiologic mechanisms. Using specific inclusion criteria, an integrative review was conducted that included data from human experimental, prospective cross-sectional, and cohort epidemiological studies that examined the association between binge drinking and CV conditions such as hypertension, myocardial infarction, stroke, and arrhythmias. Studies were identified that examined the relationship between binge drinking and CV outcomes. Collectively, findings support that binge drinking is associated with a higher risk of pre-hypertension, hypertension, myocardial infarction, and stroke in middle-aged and older adults. Binge drinking may also have adverse CV effects in young adults (aged 18-30). Mechanisms remain incompletely understood; however, available evidence suggests that binge drinking may induce oxidative stress and vascular injury and be pro-atherogenic. Public health messages regarding binge drinking need to include the effects of binge drinking on the cardiovascular system. This article is protected by copyright. All rights reserved.

KEYWORDS:

Alcohol; binge drinking; cardiovascular conditions; myocardial infarction; stroke