Thursday, 23 June 2016

2013 Chapter 46 – Biochemical Mechanisms of Fatty Liver and Bioactive Foods: Wild Foods, Bioactive Foods, Clinical Trials in Hepatoprotection


Nutrition therapy for fatty liver lowers lipid levels successfully and manages cholelithiasis and hepatic fibrosis in both alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). Awareness of bioactive foods, diets, wild foods, and nutrients in public and government policies is exciting and accepted by regulatory agencies to be introduced in both outpatient and inpatient departments in medical practice and public health. Increasing events of side effects of pharmaceuticals in treating biliary cholelithiasis and hepatic injury are worrisome and leading physicians in search of alternative means of dyslipidemia management through change in life style, behavior counseling, and proper diet schedule. Approaches for the future are focused on fatty acid transport mechanism, reducing fat accumulation in both the liver and gall bladder by dietary intervention, safe use of bioactive foods, and herbal supplements.
Keywords: Alcoholic liver disease, Bioactive foods, Fatty liver, Hepatocytes, Kupffer cells, Liver metabolism, Nonparenchymal cells, Nutrients, Wild foods