J Equine Sci. 2016;27(1):19-22. doi: 10.1294/jes.27.19. Epub 2016 Apr 12.
- 1Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
- 2Department of Veterinary Physiology, Ahmadu Bello University, Zaria, Nigeria.
Abstract
This
study aimed to evaluate the effects of a supplement that contains
resveratrol and hyaluronic acid (RH supplement) in aged lame horses. A
total of 16 horses of both sexes, aged between 15 and 22 years, weighing
between 350-450 kg and showing lameness due to arthritis of the knee,
hock, stifle, and fetlock
joints and stiffness owing to ageing were used for the study. They
comprised eight horses that were administered the RH supplement for
three weeks and eight others that served as controls and were given only
a Saccharomyces cerevisiae yeast strain used as carrier in the
supplement. Blood samples were collected from each horse before
supplementation (week 0) and at weekly intervals for the three weeks of
the experiment. Biochemical parameters including creatine kinase,
aspartate aminotransferase, urea, glucose, total cholesterol, sodium,
potassium, chloride, and calcium were measured by standard methods.
There was a significant (P˂0.05) reduction in values of creatine kinase
and glucose in the horses administered the RH supplement. It was
concluded that the RH supplement may reduce the level of these
biochemical parameters and their deleterious effects especially during
ageing in horses.
KEYWORDS:
ageing; biochemical parameters; horse; hyaluronic acid; resveratrol
