2015, Pages 119–147
Chapter 5 – Validation of Medicinal Herbs for Skin Aging
Abstract
Skin
aging is the result of programed senescence and prolonged environmental
injury to skin. Human skin is continuously exposed to environmental
influences and is therefore subjected to both intrinsic as well as
extrinsic aging processes. Aged skin is characterized by the loss of
skin tone and resilience, increased roughness and dryness, irregular
pigmentation, sunburn, accelerated skin aging, wrinkles, and several
malignant skin cancers. Plant secondary metabolites have been exploited
for their potential activities such as antiaging, antiwrinkle,
antioxidant, antiinflammatory, wound healing, skin whitening, and
anticancer activities. Several scientific validations on natural
products derived from the traditional system of medicine have been
developed in this context. Recent trends in antiaging research projected
the use of natural products derived from ancient era after scientific
validation. Therefore, an attempt has been made in this chapter to
highlight skin aging pathways of natural bioactive molecules and skin
aging management.
Keywords
- Ellagic acid;
- Matrix metalloproteinase;
- Photoaging;
- Resveratrol;
- ROS;
- Skin aging;
- UV radiation
Acknowledgments
The
authors are thankful to the Department of Science and Technology, Drug
and Pharmaceutical Research Program, Government of India, New Delhi
[DST-DPRP, File No. VI-D&P/287/08-09/TDT], for financial support for
this project to the School of Natural Product Studies, Jadavpur
University, Kolkata, India.
Copyright © 2015 Elsevier Inc. All rights reserved.
