Asian Pacific Journal of Tropical Disease
Volume 4, Supplement 1, 2014, Pages S250–S254
Document heading

In vivo evaluation of antiparasitic effects of Artemisia abrotanum andSalvia officinalis extracts on Syphacia obvelata, Aspiculoris tetrapetraand Hymenolepis nana parasites



doi:10.1016/S2222-1808(14)60449-7
Get rights and content

Abstract

Objective

To evaluate the effects of Salvia officinalis and Artemisia abrotanum extracts against digestive system parasites of mice.

Methods

The ethanol extract was prepared and dissolved in distilled water. The mebendazole was used as positive control and distilled water as negative control. After counting eggs per gram feces, infected mice with 16 eggs per gram feces contained two to three parasites of Syphacia obvelata, Aspicoloris terepetra andHymenolipis nana designated in 4 groups. The first group was given extracts of Artemisia (150 mg/kg), the second group was given Salvia extract (150 mg/kg), the third group was given mebendazole (10 mg/kg) and finally the fourth group was given distilled water (2 mL/kg).

Results

The ethanol extracts of Artemisia and Salvia plants reduced the number of parasite eggs per gram of feces. Results showed significant reduction (P-value<0.001) in the number of eggs excreted by Hymenolepis nana, Aspiculuris tetraptera, Syphacia obvelata in mice.

Conclusions

These results revealed that antiparasitic effects of Artemisia and Salvia are reasonable and these two plants might be used as antiparasitic natural products.

Keywords

  • Salvia officinalis; 
  • Artemisia abrotanum; 
  • Mice; 
  • Parasite; 
  • Syphacia obvelata; 
  • Aspicoloris terepetra;
  • Hymenolipis nana
Available online 28 Jan 2014
Foundation Project: Supported by Jiroft Branch, Islamic Azad University of Jiroft, Iran(Grant No. 1713864).
Peer reviewer: Dr. Hassan hassanzadazar, PhD of food hygiene, food control expert of food and drug deputy, Urmia university of medical science, Urmia, Iran. Tel: +989144412026, Fax: +984413455839, E-mail: h.hassanzadazar@yahoo.com
Comments: This is a good research in which the authors determined effects of two local plant extracts on three various parasites in mice. The results are interesting that S. officinalis and A. abrotanum extracts had good antiparasitic effects on three various parasite.

Corresponding author: Mahmoud Bahmani, Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran. Tel: 984412772023, Fax: 984412787814
Copyright © 2014 Asian Pacific Tropical Medicine Press. Published by Elsevier (Singapore) Pte Ltd. All rights reserved.