Volume 6, Issue SUPPL. 2, June 2013, Pages 16-20
a
NIMS University, Jaipur, Rajasthan, India
b Ravishankar College of pharmacy, Bhopal, M.P, India
b Ravishankar College of pharmacy, Bhopal, M.P, India
Abstract
Oral diseases are
major health problems with dental caries and periodontal diseases among
the most important preventable global infectious diseases. Oral health
influences the general quality of life and poor oral health is linked to
chronic conditions and systemic diseases. The association between oral
diseases and the oral micro biota is well established. The development
of dental caries involves acidogenic and aciduric Gram-positive bacteria
(mutans streptococci, lactobacilli and actinomycetes). Periodontal
diseases have been linked to anaerobic Gram-negative bacteria
(Porphyromonas gingivalis, Actinobacillus, Prevotella and
Fusobacterium). Several agents are commercially available these
chemicals can alter oral micro biota and have undesirable side-effects
such as vomiting, diarrhea and tooth staining. Hence, the search for
alternative products continues and natural phytochemicals isolated from
plants used as traditional medicines are considered as good
alternatives. In this review, plant extracts or phytochemicals that
inhibit the growth of oral pathogens, reduce the development of bio
films and dental plaque, influence the adhesion of bacteria to surfaces
and reduce the symptoms of oral diseases.
Author keywords
Dental caries; Dental plaque; Oral pathogens; Periodontal diseases; Periodontitis
Indexed keywords
EMTREE drug terms: Abies canadensis extract; Acacia
catechu extract; Albizia julibrissin extract; antibiotic agent;
Azadirachta indica extract; black pepper extract; Chelidonium extract;
chlorhexidine; Cinnamomum verum extract; cinnamon extract; Coptis
rhizome extract; Curcuma longa extract; Drosera peltata extract;
essential oil; Eucalyptus extract; Ficus bengalensis extract; Ginkgo
biloba extract; Juniperus virginiana extract; Leptospermum morrisonii
extract; Pinus virginiana extract; plant extract; propolis; Psoralea
corylifolia extract; Rosmarinus officinalis extract; Sassafras albidum
extract; syzygium aromaticum extract; Tanacetum vulgare extract; tea tree oil; Thuja plicata extract; unclassified drug; unindexed drug
EMTREE medical terms: Actinobacillus; Actinomyces;
antibacterial activity; antibiotic sensitivity; bactericidal activity;
bacterium adherence; biofilm; dental caries; dental health; diarrhea;
disease association; Fusobacterium; gingiva bleeding; gingiva disease;
gingivitis; Gram negative bacterium; Gram positive bacterium; human;
Lactobacillus; mouth flora; periodontal disease; periodontitis; plant
root; plant stem; Porphyromonas gingivalis; Prevotella; quality of life;
review; Streptococcus mutans; tooth brushing; tooth disease; tooth
hypersensitivity; tooth pain; tooth plaque; tooth staining; traditional
medicine; vomiting
Chemicals and CAS Registry Numbers: chlorhexidine, 3697-42-5, 55-56-1; propolis, 8012-89-3