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Wednesday, 4 November 2015

Dental disease and its cure: A review

Volume 6, Issue SUPPL. 2, June 2013, Pages 16-20


NIMS University, Jaipur, Rajasthan, India
Ravishankar College of pharmacy, Bhopal, M.P, India

Abstract

Oral diseases are major health problems with dental caries and periodontal diseases among the most important preventable global infectious diseases. Oral health influences the general quality of life and poor oral health is linked to chronic conditions and systemic diseases. The association between oral diseases and the oral micro biota is well established. The development of dental caries involves acidogenic and aciduric Gram-positive bacteria (mutans streptococci, lactobacilli and actinomycetes). Periodontal diseases have been linked to anaerobic Gram-negative bacteria (Porphyromonas gingivalis, Actinobacillus, Prevotella and Fusobacterium). Several agents are commercially available these chemicals can alter oral micro biota and have undesirable side-effects such as vomiting, diarrhea and tooth staining. Hence, the search for alternative products continues and natural phytochemicals isolated from plants used as traditional medicines are considered as good alternatives. In this review, plant extracts or phytochemicals that inhibit the growth of oral pathogens, reduce the development of bio films and dental plaque, influence the adhesion of bacteria to surfaces and reduce the symptoms of oral diseases.

Author keywords

Dental caries; Dental plaque; Oral pathogens; Periodontal diseases; Periodontitis

Indexed keywords

EMTREE drug terms: Abies canadensis extract; Acacia catechu extract; Albizia julibrissin extract; antibiotic agent; Azadirachta indica extract; black pepper extract; Chelidonium extract; chlorhexidine; Cinnamomum verum extract; cinnamon extract; Coptis rhizome extract; Curcuma longa extract; Drosera peltata extract; essential oil; Eucalyptus extract; Ficus bengalensis extract; Ginkgo biloba extract; Juniperus virginiana extract; Leptospermum morrisonii extract; Pinus virginiana extract; plant extract; propolis; Psoralea corylifolia extract; Rosmarinus officinalis extract; Sassafras albidum extract; syzygium aromaticum extract; Tanacetum vulgare extract; tea tree oil; Thuja plicata extract; unclassified drug; unindexed drug
EMTREE medical terms: Actinobacillus; Actinomyces; antibacterial activity; antibiotic sensitivity; bactericidal activity; bacterium adherence; biofilm; dental caries; dental health; diarrhea; disease association; Fusobacterium; gingiva bleeding; gingiva disease; gingivitis; Gram negative bacterium; Gram positive bacterium; human; Lactobacillus; mouth flora; periodontal disease; periodontitis; plant root; plant stem; Porphyromonas gingivalis; Prevotella; quality of life; review; Streptococcus mutans; tooth brushing; tooth disease; tooth hypersensitivity; tooth pain; tooth plaque; tooth staining; traditional medicine; vomiting
Chemicals and CAS Registry Numbers: chlorhexidine, 3697-42-5, 55-56-1; propolis, 8012-89-3