Article first published online: 3 JUN 2013
DOI: 10.1002/ptr.5018
Copyright © 2013 John Wiley & Sons, Ltd.
Keywords:
- shilajit;
- mumie;
- moomiyo;
- mummiyo;
- safety;
- efficacy;
- active ingredients;
- mechanisms
Shilajit
(mumie; moomiyo, mummiyo) has been used for a wide variety of illnesses
and conditions for many years. However, relatively few well-controlled
human studies have been conducted on the effects of shiliajit, although a
growing number of studies have been published in recent years involving
animal and in vitro systems. The safety of shilajit is well
documented based on animal and human studies. Various research studies
indicate that shilajit exhibits antioxidant, anti-inflammatory,
adaptogenic, immunomodulatory, and anti-dyslipidemic properties. Animal
and human studies indicate that shilajit enhances spermatogenesis.
Furthermore, animal and human data support its use as a ‘revitalizer’,
enhancing physical performance and relieving fatigue with enhanced
production of ATP. Key constituents in shilajit responsible for these
effects appear to be dibenzo-α-pyrones and fulvic acid and their
derivatives. Various mechanistic studies provide support for the above
observed effects. Additional well-controlled human and animal studies
involving the use of standardized products are needed. Copyright © 2013
John Wiley & Sons, Ltd.