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Friday 29 January 2016

Effects of bearberry, parsley and corn silk extracts on diuresis, electrolytes composition, antioxidant capacity and histopathological features in mice kidneys

Journal of Functional Foods
Volume 21, March 2016, Pages 272–282


  • a Emergency Centre, Clinical Centre of Vojvodina, Hajduk Veljkova 1, Novi Sad 21000, Serbia
  • b Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, Novi Sad 21000, Serbia
  • c Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1, Novi Sad 21000, Serbia
  • d Institute for Food Technology, University of Novi Sad, Bulevar cara Lazara 1, Novi Sad 21000, Serbia
Received 5 June 2015, Revised 5 December 2015, Accepted 8 December 2015, Available online 30 December 2015
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doi:10.1016/j.jff.2015.12.016
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Highlights

•
Corn silk, parsley and bearberry leaves.
•
Diuresis, electrolytes composition.
•
Antioxidant capacity of mice's kidneys.
•
Histopathological features of treated mice's kidneys.
•
Functional food ingredients.

Abstract

The effects of corn silk (Maydis stigma), parsley (Petroselinum crispum) and bearberry leaves (Uva ursi folium) extracts on diuresis, electrolytes composition, antioxidant capacity and histopathological features of pretreated mice kidneys were determined. The first group of ten animals drank corn silk, second parsley and third bearberry leaf extract. Fourth group was the control when animals drank water. Extracts and water were administrated ad libitum. On 0, 1st, 7th, 14th and 28th day of the experiment urine volume and electrolyte content were measured. Antioxidant status of kidneys was investigated by determining antioxidant enzymes and reduced glutathione quantity. Free radical scavenging capacity, lipid peroxidation and total antioxidant power were determined. Hystopahological examination of kidneys was performed at the end of the experiment. On the basis of the overall presented results parsley and corn silk extracts could be proposed for further investigations as new functional food ingredients with antioxidant and diuretic properties.

Keywords

  • Maydis stigma;
  • Petroselinum crispum;
  • Uvae ursi;
  • Pharmacodynamic-estimation;
  • Antioxidant status;
  • Histopathological features
Corresponding author. Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, Novi Sad 21000, Serbia. Tel.: +381 21 485 3374; fax: +381 21 450 857.
Copyright © 2015 Elsevier Ltd. All rights reserved.
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