a
Department of Periodontology, Unit of Oral Pathology, Wroclaw Medical University, 26 Krakowska Str, 50-425 Wrocław, Poland
b Department of Gynecology and Obstetrics, Faculty of Health Sciences, Wroclaw Medical University, Poland
b Department of Gynecology and Obstetrics, Faculty of Health Sciences, Wroclaw Medical University, Poland
Abstract
Most drugs pass
through the placenta because of its small weight. What remains
inadequate, is patients' awareness of pharmacotherapy during pregnancy.
There are not so many experiments showing the knowledge about
pharmacotherapy during pregnancy among women. In the present study
authors wanted to demonstrate what is the knowledge of women about drugs
toxicity in FDA pregnancy categories, the use of prescription drugs and
biological products, and what kind of drugs, supplements of diet and herbal
products were used by patients during pregnancy. The aim was also to
reveal knowledge about drugs toxicity on fetus. Questionnaire survey was
anonymous, and done by a midwife 1-3 days after parturition. Patients
were women from region of Lower Silesia (Poland),
who chose to give birth in the Clinic of Gynecology and Obstetrics,
Chalubinskiego Street in Wroclaw. Research resulted in 60 questionnaires
received from women. Percentage of patients, who had been taking
supplementation with folic acid and vitamins reached 77%. As much as 45%
of women who took part in research had used pharmacotherapy during
pregnancy. From all women, 17% declared to have taken herbal
preparations for common cold, fever, cough. Result of the study
revealed that 23% of women who took part in the study knew about the FDA
division of drugs used during pregnancy. The knowledge about possible
teratogenic effect of the drugs is not yet well established among women
after parturition. Special observations have to be done among pregnant
women for broadening the knowledge about pharmacotherapy in pregnancy
and women's treatment habits during pregnancy. 2013 © Curr. Issues
Pharm. Med. Sci.
Author keywords
Drug therapy; Drug toxicity; Herb-drug interactions; Pregnancy pharmacology
Indexed keywords
EMTREE drug terms: alpha tocopherol; amoxicillin;
ascorbic acid; biological product; cefuroxime axetil; chlorquinaldol;
drotaverine; ferrous fumarate; folic acid; furazidin; herbaceous agent;
iodine; iron; levothyroxine; magnesium; manganese; metronidazole;
nifuratel; nystatin; prescription drug; progesterone; vitamin; vitamin B
complex; vitamin D; zinc
EMTREE medical terms: article; awareness; birth;
clinical research; common cold; coughing; diet supplementation; drug
safety; female; fetotoxicity; fetus; fever; food and drug
administration; gynecologist; health survey; herbal medicine; human; knowledge; major clinical study; midwife; Poland; pregnant woman; prenatal drug exposure; prescription; questionnaire; teratogenicity
Chemicals and CAS Registry Numbers: alpha tocopherol,
1406-18-4, 1406-70-8, 52225-20-4, 58-95-7, 59-02-9; amoxicillin,
26787-78-0, 34642-77-8, 61336-70-7; ascorbic acid, 134-03-2, 15421-15-5,
50-81-7; cefuroxime axetil, 64544-07-6; chlorquinaldol, 72-80-0;
drotaverine, 14009-24-6, 861-27-8, 985-12-6; ferrous fumarate, 141-01-5,
7705-12-6; folic acid, 59-30-3, 6484-89-5; furazidin, 1672-88-4;
iodine, 7553-56-2; iron, 14093-02-8, 53858-86-9, 7439-89-6;
levothyroxine, 51-48-9; magnesium, 7439-95-4; manganese, 16397-91-4,
7439-96-5; metronidazole, 39322-38-8, 443-48-1; nifuratel, 4936-47-4;
nystatin, 1400-61-9, 34786-70-4, 62997-67-5; progesterone, 57-83-0;
zinc, 14378-32-6, 7440-66-6
ISSN: 2084980XSource Type: Journal
Original language: English
DOI: 10.12923/j.2084-980X/26.2/a.20Document Type: Article
Duś, I.M.; Department of Periodontology, Unit of Oral Pathology,
Wroclaw Medical University, 26 Krakowska Str, 50-425 Wrocław, Poland;
email:irena.dus@gmail.com
© Copyright 2013 Elsevier B.V., All rights reserved.
© Copyright 2013 Elsevier B.V., All rights reserved.