Fitoterapia. 2015 Jun;103:9-26. doi: 10.1016/j.fitote.2015.03.012. Epub 2015 Mar 14.
- 1National
Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis,
Tunisia; Higher Agronomic Institute of Chott-Mariem, BP 47, 4042 Chott
Meriem, Sousse, Tunisia. Electronic address: bochra_laribi@yahoo.fr.
- 2National Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis, Tunisia.
- 3National
Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis,
Tunisia; Higher Agronomic Institute of Chott-Mariem, BP 47, 4042 Chott
Meriem, Sousse, Tunisia.
Abstract
Coriander (Coriandrum sativum L.),
a member of the Apiaceae family, is among most widely used medicinal
plant, possessing nutritional as well as medicinal properties. Thus, the
aim of this updated review is to highlight the importance of coriander as a potential source of bioactive constituents
and to summarize their biological activities as well as their different
applications from data obtained in recent literature, with critical
analysis on the gaps and potential for future investigations. A
literature review was carried out by searching on the electronic
databases including PubMed, Scopus, ScienceDirect, and Google Scholar
for studies focusing on the biological and pharmacological activities of
coriander seed and herb bioactive constituents. All recent English-language articles published between 2000 and 2014 were searched using the terms 'C. sativum', 'medicinal plant', 'bioactive constituents', and 'biological activities'. Subsequently, coriander
seed and herb essential oils have been actively investigated for their
chemical composition and biological activities including antimicrobial,
antioxidant, hypoglycemic, hypolipidemic, anxiolytic, analgesic,
anti-inflammatory, anti-convulsant and anti-cancer activities, among
others. Although coriander
has been reported to possess a wide range of traditional medicinal
uses, no report is available in its effectiveness use in reactive airway
diseases such as asthma and bronchiolitis. In brief, the information
presented herein will be helpful to create more interest towards this
medicinal species by defining novel pharmacological and clinical
applications and hence, may be useful in developing new drug
formulations in the future or by employing coriander bioactive constituents in combination with conventional drugs to enhance the treatment of diseases such as Alzheimer and cancer.
Copyright © 2015 Elsevier B.V. All rights reserved.
KEYWORDS:
(+)-Linalool
(S)-(+)-linalool (PubChem CID:6549); (E)-2-decenal (PubChem
CID:2583345); (E)-2-dodecen-1-ol (PubChem CID:90733); (E)-2-undecen-1-ol
(PubChem CID:61968); 2-Decen-1-ol (PubChem CID:5364942); Anethole
(PubChem CID:637563); Bioactive constituents; Biological activities; Camphor (PubChem CID:2537); Citronellal (PubChem CID:7794); Coriandrum sativum L;
Dec-9-en-1-ol (PubChem CID:25612); Decanal (PubChem CID:8175); Decanol
(PubChem CID:8174); Geraniol (PubChem CID:637566); Geranyl acetate
(PubChem CID:1549026); Herb; Limonene (PubChem CID:22311);
Linalyl-acetate (PubChem CID:8294); Neryl acetate (PubChem CID:7780);
Nonane (PubChem CID:8141); Seed; Tetradecenol (PubChem CID:120110);
Tridecanal (PubChem CID:31291); Tridecanol (PubChem CID:25311);
Undecanal (PubChem CID:8186); Undecanol (PubChem CID:8184);
cis-Dihydrocarvone (PubChem CID:443167); n-Tetradecanol (PubChem
CID:8209); p-Cymene (PubChem CID:7463); α-Cedrene (PubChem CID:6431015);
α-Farnasene (PubChem CID:5281516); α-Phellandrene (PubChem CID:7460);
α-Pinene (PubChem CID:6654); β-Pinene (PubChem CID:14896); γ-Terpinene
(PubChem CID:7461
