- 1General Physician, Student Basij Medicinal Plants
Research Center, Guilan University of Medical Sciences, Rasht, Iran /
Young Researchers Club, Rasht Branch, Islamic Azad University, Rasht,
Iran.
- 2Medical Student, Student Basij Medicinal Plants
Research Center, Guilan University of Medical Sciences, Rasht, Iran /
Young Researchers Club, Rasht Branch, Islamic Azad University, Rasht,
Iran.
- 3General Physician, Student Basij Medicinal Plants Research Center, Guilan University of Medical Sciences, Rasht, Iran.
- 4Department
of Chemistry, University of Guilan, Rasht, Iran / Young Researchers
Club, Rasht Branch, Islamic Azad University, Rasht, Iran.
- 5Urology Resident, Shahid Beheshti University of Medical Sciences, Shoahad-e-Tajrish Hospital, Tehran, Iran.
Abstract
Enterococcus
fecalis is responsible for majority of enterococci infections and can
cause clinical disorders in adult and pediatrics. In order to adverse
effects of synthetic drugs, it has made a positive attitude toward
alternative and complementary medicine. Ruta graveolens has a wide
therapeutic application for various diseases. Aim of this study was to
see the effect of this herb on Enterococcus fecalis growth. In this
investigation we used standard Enterococcus fecalis. Effect of
hydro-alcoholic, aqueous and methanolic extracts of Ruta graveolens on
growth of bacteria has been evaluated by disc diffusion and serial
dilution method and compared with eight prevalent antibiotics. None of
disks with different extracts in the range of 50 to 400μ/ μl show any
non-growth hallo. Disks with 500μg of all type extracts in comparison
with antibiotic
disks did not avoid from growth of bacteria. Third test showed the
growth of bacteria and ineffectiveness of various amount of extracts. It
seems that this ineffectiveness is because of low antibacterial
substance against the bacteria in extracts of the herb and high
resistant nature of Enterococcus fecalis to antibiotics and it needs
more studies.
