Study of Antimicrobial and Cytotoxic Potential of the Oyster Mushroom Pleurotus ostreatus cv. Florida (Agaricomycetes).

Int J Med Mushrooms. 2016;18(4):321-5. doi: 10.1615/IntJMedMushrooms.v18.i4.50.

Ganeshpurkar A¹, Bhadoriya SS², Pardhi P¹, Jain AP³, Rai G³.

Author information

• ¹Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, M.P., India.
• ²Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, M.P., India; Sun Institute of Pharmaceutical Education and Research, Bhind, M.P., India.
• ³Department of Pharmacy, Guru Ramdas Khalsa Institute of Science & Technology, Jabalpur, M.P., India.

Abstract

This work was undertaken to evaluate in vitro antimicrobial and cytotoxic potential of Pleurotus ostreatus cv. Florida. Mushroom basidiocarps were extracted in water:ethanol (1:1, v/v), and the resulting extract was subjected to antimicrobial studies against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella oxytoca, Bacillus subtilis, and Candida albicans. Cytotoxic potential on viable human leukocytes was studied. In vitro results showed excellent antimicrobial and cytotoxic potentials of the mushroom extract. Thus, functional properties of P. ostreatus cv. Florida could be used in the search for novel therapeutics.

PMID:

27481298

DOI:

10.1615/IntJMedMushrooms.v18.i4.50