Antifungal activity of 10 Guadeloupean plants.

Biabiany M¹, Roumy V, Hennebelle T, François N, Sendid B, Pottier M, Aliouat el M, Rouaud I, Lohézic-Le Dévéhat F, Joseph H, Bourgeois P, Sahpaz S, Bailleul F.

Author information

Abstract

Screening of the antifungal activities of ten Guadeloupean plants was undertaken to find new extracts and formulations against superficial mycoses such as onychomycosis, athlete's foot, Pityriasis versicolor, as well as the deep fungal infection Pneumocystis pneumonia. For the first time, the CMI of these plant extracts [cyclohexane, ethanol and ethanol/water (1:1, v/v)] was determined against five dermatophytes, five Candida species, Scytalidium dimidiatum, a Malassezia sp. strain and Pneumocystis carinii. Cytotoxicity tests of the most active extracts were also performed on an HaCat keratinocyte cell line. Results suggest that the extracts of Bursera simaruba, Cedrela odorata, Enterolobium cyclocarpum and Pluchea carolinensis have interesting activities and could be good candidates for developing antifungal formulations.
Copyright © 2012 John Wiley & Sons, Ltd.

KEYWORDS:

Bursera; Cedrela; Enterolobium; Pluchea; Pneumocystis; antifungal extract

Phytotherapy in the Management of Diabetes and Hypertension

Editor(s): Mohamed Eddouks

Co-Editor(s): Debprasad Chattopadhyay

DOI: 10.2174/97816080501471120101

eISBN: 978-1-60805-014-7
ISBN: 978-1-60805-567-8

Indexed in: Scopus

Chapter PDF Price: US $15

Diabetes, Hypertension and Cardiovascular Disease-An Unsolved Enigma

Author(s): Arpita Chakraborty and Maitree Bhattacharyya
Chapter DOI: 10.2174/9781608050147112010007
Page: 97-130 (34)

Abstract:

Diabetes is a major public health problem that is approaching epidemic proportions globally. Worldwide the prevalence of chronic, non-communicable diseases is increasing at an alarming rate. Cardiovascular diseases (CVDs) are the major causes of mortality in persons with diabetes, and many factors, including hypertension, contribute to this high prevalence of CVD. Hypertension is approximately twice as frequent in patients with diabetes compared with patients without the disease. Conversely, recent data suggest that hypertensive persons are more predisposed to the development of diabetes than are normotensive persons. Co-existence of diabetes mellitus and hypertension increases the risk of macro- and micro-vascular complications. In this review attempt has been made to explore the risk factors which can be helpful to prevent hyperglycemia and related manifestation of Type 2 diabetes. Both biochemical and genetic diagnostic markers identified till now have been catalogued to describe the status of pathogenesis in hyperglycemic subjects.

Keywords:

Type 2 Diabetes, Cardiovascular Disease, Hypertension, Biochemical risk factors, Genetic susceptibility.

Affiliation:

Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata-700019, India

- See more at: http://www.eurekaselect.com/104831/chapter/diabetes,-hypertension-and-cardiovascular-disease-an-unsolved-enigm#sthash.v4MeNvke.dpuf

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Monday, 6 April 2015