2015, Pages 1–28
Chapter 1 – Quality Related Safety Issue-Evidence-Based Validation of Herbal Medicine Farm to Pharma
- doi:10.1016/B978-0-12-800874-4.00001-5
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Abstract
Because
of their unique effects and relatively low side effects, herbal
medicine has been gaining popularity all over the world. Quality control
is a challenge to ensure safety, efficacy, and batch-to-batch
consistency of herbal products due to the complexity of phytochemical
constituents. Generally, it is believed that the risk associated with
herbal drugs is very less, but several reports on serious reactions are
indicating the need for the development of safety profiles; effective
regulatory guidelines; and quality control systems for authentication,
isolation, and standardization of herbal medicine. Lack of strict
guidelines on the assessment of safety and efficacy, quality control,
safety monitoring, and knowledge on traditional medicine (TM) are the
main aspects that are found in different regulatory systems. Proper
validation of herbs used in TM needs to be done for their promotion and
development.
Keywords
- Herb–drug interaction;
- Marker profiling;
- Pharmacovigilance;
- Quality control;
- Safety evaluation;
- Standardization
Acknowledgments
The
authors wish to express their gratitude to the National Medicinal Plant
Board (NMPB), Department of AYUSH, Ministry of Health and Family
Welfare, Government of India, for providing financial assistance to the
School of Natural Product Studies, Jadavpur University, through project
grant [F. No.: Z. 18017/187/CSS/R&D/WB-01/2009-10-NMPB].
Copyright © 2015 Elsevier Inc. All rights reserved.
