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Saturday, 11 April 2015

Chapter 18 – Botanicals as Medicinal Food and Their Effects against Obesity

Chapter 18 – Botanicals as Medicinal Food and Their Effects against Obesity


Abstract

Obesity is one type of metabolic syndrome, causes excess fat accumulation in the torso, resulting health problems like diabetes, hypertension, and dyslipidemia. As per World Health Organization, large population of the world is suffering from obesity and obesity associated disorders. R&D sectors of pharmaceutical companies around the globe are making several efforts to find effective antiobesity drugs. Despite that not many of the drug candidates pass all phases of clinical trials. Researchers in this field are instantly concerned to hunt nonconventional approach to the prevention and treatment of obesity. Herbs as food have a promising future in this regard. It has a beneficial effect over conventional food because it has provided therapeutic value in addition to nutritional supplement, in a way relevant to improved state of wellness and well-being which in turn reduce the risk of disease. Many plants and plant-derived products have been discussed in this chapter, which have potential activity against metabolic disorder such as obesity, hyperlipidemia, fatty liver, insulin resistance, and hyperglycemia and they exert their effect through multiple mechanisms.

Keywords

  • Adipose tissue;
  • Antiobesity;
  • Dietary fiber;
  • Functional food;
  • Medicinal plants;
  • Organosulfurans;
  • Phytochemical

Acknowledgment

The authors wish to express their gratitude to Indian Council of Medical Research (File-45/43/2010/BMS/TRM) Govt. of India, New Delhi, for providing financial support through Research Associateship to Kakali Mukherjee.