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Friday, 4 December 2015

1791 Composer Wolfgang Amadeus Mozart dies in Vienna.

Korean Circ J. 2010 Dec; 40(12): 611–613.
Published online 2010 Dec 31. doi:  10.4070/kcj.2010.40.12.611
PMCID: PMC3025332

Infective Endocarditis and Phlebotomies May Have Killed Mozart

Abstract

Thirty-five year-old Amadeus Mozart died in Vienna after an acute illness that lasted only 15 days but no consensus has been reached on the cause of his death. From many letters written by his farther it is almost certain that he experienced at least three episodes of acute rheumatic fever attack in his childhood, and a relapse of rheumatic fever was suggested to have killed Mozart, although death from acute rheumatic fever is very rare in adults. His last illness was characterized by high fever, massive edema, vomiting and skin rash. His last illness can be explained by infectious endocarditis and heart failure. During his last hours, he was given phlebotomy, possibly for the third time in two weeks, and soon after he became unconscious and died. As such, phlebotomy performed on a man dehydrated by high fever and vomiting may have caused systemic shock. In summary, Mozart probably died from chronic rheumatic heart disease complicated by infective endocarditis and heart failure, and repeated phlebotomy-induced hypovolemic shock.
Keywords: Infective endocarditis, Bloodletting, Hypovolemic shock

Introduction

Wolfgang Amadeus Mozart died on 5 December 1791 after having suffered 15 days of acute and mysterious illness. After his death, his doctor, Franz Closset, made the diagnosis of "hitziges Frieselfieber" (acute or severe miliary fever) which was a common diagnosis made on patients with fever and skin rash at that time. There was no reason to suspect any foul play and autopsy was not performed.
Seventeen ninety-one was one of Mozart's most productive years and he led an active life traveling widely and conducting his music, but became bed-ridden only 15 days before his death. The last days of Mozart was described by Sophie Heibel, Mozart's sister in-law, to Nissen who was writing Mozart's biography and ultimately married Mozart's widow.1) In her letter to Nissen, Heibel described "when the doctor was called in, he bled Mozart and put cold compresses on his burning head, whereupon his strength declined rapidly and he fell unconscious and never came around again".2) Indeed, Mozart died 2 hours after being bled. However, no consensus has been reached on the cause of Mozart's death.

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