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Tuesday, 19 January 2016

In Vitro Anthelmintic Activity of Mucuna pruriens (DC) and Canarium schweinfurthii (Engl) on Ascaris suum

https://www.researchgate.net/publication/275033929_In_Vitro_Anthelmintic_Activity_of_Mucuna_pruriens_DC_and_Canarium_schweinfurthii_Engl_on_Ascaris_suum


Open Access Library Journal 02/2015; 2(02). DOI: 10.4236/oalib.1101102

ABSTRACT
The in vitro anthelmintic evaluation of the crude extracts and solvent partitions on Pheretima post-huma and Ascarissuum (eggs and L2 stage) respectively showed significant results at the same concentration (10, 20, 40 and 80 mg/ml). This study provides a clear evidence for usage of Mucuna pruriens and Canarium schweinfurthii as an anthelmintic. The most potent ovicidal partition of C. schweinfurthii (Engl) leaves and bark and leaves of M. pruriens (DC) is hexane (100.00 ± 0.33), chloroform (98.20 ± 0.12) and chloroform (98.70 ± 0.88) partitioned crude respectively at 80 mg/ml while the most potent larvicidal partition is hexane (0.06%), chloroform (0.1%) and chloroform (0.2%). The active compounds are predominantly in the non-polar solvent which supports the te-gumental diffusing activity of the compounds.