In 1645, the dying Tsar Mikhail Romanov was examined by his German 
doctors, and prescribed, via Latin instructions, Chinese rhubarb, 
Alexandrine Senna, local Juniper berries, unicorn horn, and American 
sassafras, a treatment recorded in exacting detail by Russian 
bureaucrats in Russian. Such a circumstance might seem odd. Works on 
early modern science and medicine commonly present the Russian empire as
 isolated, if they devote any space to the region at all. On the 
contrary, the Russian court imported its official medicine from Western 
Europe, recruiting experts and sourcing texts and supplies from its 
major diplomatic and trading partners. The treatment of Mikhail 
Fedorovich demonstrates Russia’s wider medical links. Indeed, the 
combination of medicaments from across the early modern world, and the 
use of multiple languages in this case was an entirely normal occurance 
at the early modern Russian court.
https://www.mpiwg-berlin.mpg.de/en/research/projects/DeptII_Griffin_RecipesDrugs 
