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Friday, 5 February 2016

Phytochemical profile and therapeutic potential of Viscum album L.

Volume 30, Issue 4, 16 February 2016, Pages 373-385


a  Department of Pharmacognosy, Medical University of Bialystok, Bialystok, Poland
b  Hospital in Blachownia, Blachownia, 

Abstract

Viscum album L., the European mistletoe, is a common species from the Viscaceae family. This evergreen hemiparasitic shrub grows on various trees and contains diverse, biologically active substances. Its chemical composition may vary depending on the time of harvest, species of the host tree and the manufacturing process. Among well-described and most active phytochemicals identified in V. album are lectins and viscotoxins, which play substantial role in cancer treatment because of their apoptotic and cytotoxic effects. Another group of compounds found in mistletoe are phenolic acids, phenylpropanoids and flavonoids with antioxidant and anti-inflammatory activities, which decrease blood pressure. Other mistletoe components include, among others, triterpenes with cytotoxic and apoptotic properties, and phytosterols, oligo- and polysaccharides. Extracts from the plant, especially aqueous, are applied in traditional and official medicine, among others in treating hypertension or arthritis. Potentially, it can also be used as a hepatoprotective or a sedative drug. © 2015 Taylor & Francis.

Author keywords

biologically activity; chemical composition; European mistletoe; ssp. abietis; ssp. austriacum; Viscum album L. ssp. album