a
Department of Biochemical Sciences, Charles University in Prague,
Faculty of Pharmacy, Heyrovského 1203, Hradec Králové, Czech Republic
b Laboratory of Plant Biotechnologies, Institute of Experimental Botany, Czech Academy of Sciences, Rozvojová 263, Praha 6, Czech Republic
b Laboratory of Plant Biotechnologies, Institute of Experimental Botany, Czech Academy of Sciences, Rozvojová 263, Praha 6, Czech Republic
Abstract
Veterinary drugs used
for treatment and prevention of diseases in animals represent important
source of environmental pollution due to intensive agri- and
aquaculture production. The drugs can reach environment through the
treatment processes, inappropriate disposal of used containers, unused
medicine or livestock feed, and manufacturing processes. Wide scale of
veterinary pharmaceuticals e.g. antibiotics, antiparasitic and
antifungal drugs, hormones, anti-inflammatory drugs, anaesthetics,
sedatives etc. enter the environment and may affect non-target organisms
including plants. This review
characterizes the commonly used drugs in veterinary practice, outlines
their behaviour in the environment and summarizes available information
about their toxic effect on plants. Significant influence of many antibiotics and hormones on plant
developmental and physiological processes have been proved. However,
potential phytotoxicity of other veterinary drugs has been studied
rarely, although knowledge of phytotoxicity of veterinary drugs may help
predict their influence on biodiversity and improve phytoremediation
strategies. Moreover, additional topics such as long term effect of low
doses of drugs and their metabolites, behaviour of mixture of veterinary
drugs and other chemicals in ecosystems should be more thoroughly
investigated to obtain complex information on the impact of veterinary
drugs in the environment. © 2015 Elsevier Ltd.
Author keywords
Environmental impact; Growth promoters; Phytotoxicity; Veterinary antibiotics
Indexed keywords
Engineering controlled terms: Agriculture; Anesthetics;
Antibiotics; Aquaculture; Biodiversity; Bioremediation; Endocrinology;
Environmental impact; Hormones; Veterinary medicine
Anti-inflammatory drugs; Environmental pollutions;
Growth promoters; Inappropriate disposals; Physiological process;
Phytotoxicity; Veterinary antibiotic; Veterinary pharmaceuticals
Engineering main heading: Drug dosage
Species Index: Animalia
