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Pixie Glow Tonic ($15)
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Aqua, Aloe Barbadensis Leaf Juice, Hamamelis Virginiana (Witch Hazel)
Leaf Extract, Aesculus Hippocastanum (Horse Chestnut) Seed Extract,
Glycolic Acid, Ammonium Glycolate, Glycerin, Butylene Glycol, Hexylene
Glycol (and) Fructose (and) Glucose (and) Sucrose (and) Urea (and)
Dextrin (and) Alanine (and) Glutamic Acid (and) Aspartic Acid (and)
Hexyl Nicotinate, Panax Ginseng Root Extract, Phenoxyethanol, Sodium
Benzoate, Biotin, Polysorbate 20, Fragrance.
Herb extracts and collagen hydrolysate improve skin damage resulting from ultraviolet-induced aging in hairless mice.
- 1a
Laboratory of Applied Protein Chemistry, Faculty of Agriculture , Tokyo
University of Agriculture and Technology , Fuchu-shi , Japan.
Abstract
We examined the effect of the daily ingestion of herb extract from Eucommia ulmoides leaves and Korean ginseng on skin damage induced by repeated UV irradiation of hairless mice. The herb extract was orally administered to mice at a dose of 1000 mg/kg/day. The hydration of mice dorsal skin decreased significantly with repeated UV irradiation, but did not decrease when the herb extract
was administered for seven weeks. Transepidermal water loss (TEWL)
increased with UV irradiation, but decreased with the administration of
dietary herb extract.
These effects were more pronounced when combined with the
administration of collagen hydrolysate. Geniposidic acid from E.
ulmoides leaves and ginsenoside Rg1 from Korean ginseng reduced TEWL and increased the skin moisture content of UV-damaged skin on hairless mice, respectively. We concluded that this dietary herb extract reduced the skin damage caused by UV-induced aging, with geniposidic acid and ginsenoside Rg1 detected in the blood.
KEYWORDS:
Eucommia ulmoides leaves; Korean ginseng; TEWL (transepidermal water loss); photoaging; skin hydration
